Ethyl 2,2-difluoro-2-(quinolin-2-yl)acetate CAS 294181-97-8
| CAS No. | 294181-97-8 |
| Molecular Formula | C13H11F2NO2 |
| Molecular Weight | 251.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Ethyl 2,2-difluoro-2-(quinolin-2-yl)acetate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Ethyl 2,2-difluoro-2-(quinolin-2-yl)acetate (CAS 294181-97-8), a certified reference material (molecular formula C13H11F2NO2, MW 251.23 g/mol) for analytical method development and quality control.
Ethyl 2,2-difluoro-2-(quinolin-2-yl)acetate (C13H11F2NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H11F2NO2 |
| Molecular Weight | 251.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Ethyl Standards
- 6,8-Difluoro-2-methyl-1-(2-oxopropyl)quinolin-4(1H)-one (CAS 1211719-87-7)
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Recommended Standards
- cis-3-[(tert-butoxycarbonylamino)methyl]-2,2-difluoro-cyclopropanecarboxylic acid (CAS 2218437-05-7)
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- 3-(((Tert-butoxycarbonyl)amino)methyl)-2,2-difluorocyclopropane-1-carboxylic acid (CAS 2137627-21-3)
- N-(2,4-Difluorophenyl)-2,5-dimethylfuran-3-carboxamide (CAS 691850-11-0)
- Methyl 4-methyl-4H-furo[3,2-b]pyrrole-5-carboxylate (CAS 164667-61-2)
- N-BOC-N'-BOC-4,4'-BIPIPERIDINE (CAS 165528-89-2)
- 2,5-Dioxa-8-azaspiro[3.5]nonane oxalate (CAS 1706458-74-3)
- Ethyl 4-oxo-2-(phenylamino)-4,5-dihydrofuran-3-carboxylate (CAS 58337-16-9)
- (2R,3R,4S,5R)-2-(2,6-Diamino-8-bromo-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol (CAS 81102-44-5)
- 3-(Trifluoromethyl)-L-phenylalanine (CAS 14464-68-7)
- N-pentyltetrahydro-2H-pyran-4-amine (CAS 1154893-52-3)
- 2-Chloro-8-methylquinoline (CAS 4225-85-8)
- (4-Fluorobenzyloxy)acetic acid (CAS 496975-12-3)
- Semaglutide Impurity 138 (CAS CATO-C4X-2226138)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com