5-Chloro-7-[(4-methylpiperidin-1-yl)methyl]quinolin-8-ol CAS 294675-78-8
| CAS No. | 294675-78-8 |
| Molecular Formula | C16H19ClN2O |
| Molecular Weight | 290.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 5-Chloro-7-[(4-methylpiperidin-1-yl)methyl]quinolin-8-ol (CAS 294675-78-8), a certified reference material (molecular formula C16H19ClN2O, MW 290.79 g/mol) for analytical method development and quality control.
5-Chloro-7-[(4-methylpiperidin-1-yl)methyl]quinolin-8-ol (C16H19ClN2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), 5-Chloro-7-[(4-methylpiperidin-1-yl)methyl]quinolin-8-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H19ClN2O |
| Molecular Weight | 290.79 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 2-[chloro(phenyl)methyl]-5-(2-cyclopentylethyl)-1,3,4-oxadiazole (CAS 1096913-02-8)
- [1-(2-Chloro-acetyl)-piperidin-4-yl]-methyl-carbamic acid tert-butyl ester (CAS 1353977-70-4)
- [(R)-1-(2-Chloro-acetyl)-pyrrolidin-3-yl]-carbamic acid tert-butyl ester (CAS 1353984-27-6)
- [(S)-1-(2-Chloro-acetyl)-pyrrolidin-2-ylmethyl]-methyl-carbamic acid tert-butyl ester (CAS 1353994-96-3)
- 9-Chloro-5-isobutyl-2,3,5,6-tetrahydro-1H-azepino[4,5-b]indol-4-one (CAS 1380571-66-3)
- 4-Chloro-6-(2-(methylsulfonyl)propan-2-yl)thieno[3,2-d]pyrimidine (CAS 1482914-42-0)
- 4-(2-Chloro-acetylamino)-piperidine-1-carboxylic acid tert-butyl ester (CAS 865432-01-5)
- 8-Chloro-3,3,11-trimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one (CAS 946387-35-5)
Recommended Standards
- 7-(Azepan-1-ylmethyl)-5-chloroquinolin-8-ol (CAS 315234-92-5)
- 1,1,1-Trifluoro-5-methylheptane-2,4-dione (CAS 33284-45-6)
- 1-((4-Chlorophenyl)sulfonyl)-2-(methylthio)-4,5-dihydro-1H-imidazole (CAS 673476-74-9)
- ACP-105 (CAS 899821-23-9)
- 3-(Tert-butyl)-1-isopropyl-1H-pyrazole-4-carbaldehyde (CAS 1249176-24-6)
- 4-Chloro-3-(n-(pyridin-3-ylmethyl)sulfamoyl)benzoic acid (CAS 731797-74-3)
- 3-Chloro-4-methoxy-2-methylbenzenesulfonyl chloride (CAS 2385031-64-9)
- Kushenol I (CAS 99119-69-4)
- Ethylene-ß-ionol D3 (CAS 77265-43-1)
- (R)-2-Amino-2-[(5-fluoresceinyl)aminocarbonyl]ethyl Methanethiosulfonate, Trifluoroacetic Acid Salt (CAS 1356019-48-1)
- 3-chloro-N-(4-chloro-3-methoxyphenyl)propanamide (CAS 915920-71-7)
- Azilsartan Impurity 2 (CAS 1403474-76-9)
- N-(6-Bromo-8-ethylquinolin-5-yl)benzamide (CAS 95813-71-1)
- Semaglutide impurity 89 (CAS CATO-C4X-222689)
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