5-Amino-2-phenyl-1H-1,2,4-triazol-3(2H)-one CAS 29472-94-4

Purity 97%+In StockPharmaceutical Standards
CAS No.29472-94-4
Molecular FormulaC8H8N4O
Molecular Weight176.18 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-Amino-2-phenyl-1H-1,2,4-triazol-3(2H)-one CAS 29472-94-4 chemical structure

Description

The occurrence of 5-Amino-2-phenyl-1H-1,2,4-triazol-3(2H)-one is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

5-Amino-2-phenyl-1H-1,2,4-triazol-3(2H)-one (CAS 29472-94-4), molecular formula C8H8N4O and molecular weight 176.18 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 5-Amino-2-phenyl-1H-1,2,4-triazol-3(2H)-one (C8H8N4O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 5-Amino-2-phenyl-1H-1,2,4-triazol-3(2H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC8H8N4O
Molecular Weight176.18 g/mol
AppearanceOff-white to pale yellow crystalline powder. (faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1965
Nitrogen Atoms4

Related Amino Standards

Recommended Standards

Why CATO?