5-Cyclopropylthiophene-2-carboxylic acid CAS 29481-28-5
| CAS No. | 29481-28-5 |
| Molecular Formula | C8H8O2S |
| Molecular Weight | 168.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Cyclopropylthiophene-2-carboxylic acid (CAS 29481-28-5) is a high-purity analytical reference standard with the molecular formula C8H8O2S and a molecular weight of 168.21 g/mol.
5-Cyclopropylthiophene-2-carboxylic acid (C8H8O2S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Cyclopropylthiophene-2-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H8O2S |
| Molecular Weight | 168.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
| Sulfur Atoms | 1 |
Related Cyclopropylthiophene Standards
- 4-Cyclopropylthiophene-2-carboxylic acid (CAS 1252903-38-0)
- 5-Cyclopropylthiophene-3-carboxylic acid (CAS 1518721-51-1)
- 2-Cyclopropylthiophene-3-carboxylic acid (CAS 2104675-28-5)
- 3-Cyclopropylthiophene-2-carboxylic acid (CAS 29488-33-3)
- N-cyclopropylthiophene-3-carboxamide (CAS 1090897-27-0)
- Methyl 5-cyclopropylthiophene-2-carboxylate (CAS 1021432-60-9)
- Methyl 3-cyclopropylthiophene-2-carboxylate (CAS 1871848-03-1)
- Methyl 4-cyclopropylthiophene-2-carboxylate (CAS 2111296-73-0)
Recommended Standards
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