4,6-Bis(4-fluorophenoxy)-5-nitropyrimidine CAS 294849-15-3
| CAS No. | 294849-15-3 |
| Molecular Formula | C16H9F2N3O4 |
| Molecular Weight | 345.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4,6-Bis(4-fluorophenoxy)-5-nitropyrimidine is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 4,6-Bis(4-fluorophenoxy)-5-nitropyrimidine (CAS 294849-15-3), a certified reference material (molecular formula C16H9F2N3O4, MW 345.26 g/mol) for analytical method development and quality control.
The molecular framework of 4,6-Bis(4-fluorophenoxy)-5-nitropyrimidine (C16H9F2N3O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H9F2N3O4 |
| Molecular Weight | 345.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Bis Standards
- 2-(2-Fluorophenoxy)-N-(3-(furan-2-yl)-1-(2-hydroxyethyl)-1H-pyrazol-5-yl)acetamide (CAS 1219842-50-8)
- 4-(4-Fluorophenoxy)-5-methanesulfonyl-2-phenylpyrimidine (CAS 478080-85-2)
- 2-(2-Fluorophenoxy)-N-((5-(4-fluorophenyl)isoxazol-3-yl)methyl)acetamide (CAS 953010-59-8)
- Methyl 5-(4-(4-Fluorophenoxy)phenyl)-3-aminothiophene-2-carboxylate (CAS 1159981-26-6)
- 2-(4-Fluorophenoxy)-N-(1-(furan-2-ylmethyl)-1H-pyrazol-5-yl)butanamide (CAS 1179428-67-1)
- 7-(2-(4-Fluorophenoxy)ethoxy)-4-hydroxyquinoline-3-carboxylic acid (CAS 78105-15-4)
- 2-(2-Fluorophenoxy)-N-(thiophen-3-ylmethyl)-N-(2,2,2-trifluoroethyl)acetamide (CAS 1286710-21-1)
- N-({2-[2-(4-Fluorophenoxy)acetyl]hydrazino}carbothioyl)benzenecarboxamide (CAS 1022873-90-0)
Recommended Standards
- 3-bromo-4-phenyl-3,4-dihydro-2H-[1,3]thiazino[3,2-a]benzimidazole (CAS 750570-81-1)
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- 3,5-Dichloro-5-(5,5-dimethyl-1,3-dioxan-2-yl)valerophenone (CAS 898757-11-4)
- O-Desmethyl Florasulam (CAS 292085-54-2)
- Ethyl 4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridine-3-carboxylate hydrochloride (CAS 912265-91-9)
- Devazepide (CAS 103420-77-5)
- (S)-Hexahydropyridazine-3-carboxylic acid (CAS 64044-11-7)
- 3-(4-Cyanobutanoyl)benzonitrile (CAS 898767-60-7)
- Methyl 5-phenylnicotinate (CAS 10177-13-6)
- 3-Phenyl-2-(4,4,4-trifluoro-3-oxo-but-1-enylamino)-propionic acid (CAS 133992-79-7)
- (S)-3-amino-2-(3-chlorobenzyl)propanoic acid (CAS 914644-78-3)
- Dimethyl sulfoxide-<SUP>13</SUP>C<SUB>2</SUB> (CAS 136321-15-8)
- Methyl 1-tert-butyl-2-methyl-1,3-benzodiazole-5-carboxylate (CAS 1414029-55-2)
- D-Phe6-Tirzepatide (CAS CATO-CPTD788925)
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