Ethyl 2-methyl-6-oxo-4-[4-(trifluoromethoxy)phenyl]-1,4,5,6-tetrahydro-3-pyridinecarboxylate CAS 294853-31-9
| CAS No. | 294853-31-9 |
| Molecular Formula | C16H16F3NO4 |
| Molecular Weight | 343.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Ethyl 2-methyl-6-oxo-4-[4-(trifluoromethoxy)phenyl]-1,4,5,6-tetrahydro-3-pyridinecarboxylate (CAS 294853-31-9), molecular formula C16H16F3NO4 and molecular weight 343.30 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Ethyl 2-methyl-6-oxo-4-[4-(trifluoromethoxy)phenyl]-1,4,5,6-tetrahydro-3-pyridinecarboxylate (C16H16F3NO4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Ethyl 2-methyl-6-oxo-4-[4-(trifluoromethoxy)phenyl]-1,4,5,6-tetrahydro-3-pyridinecarboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H16F3NO4 |
| Molecular Weight | 343.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- 4,4,4-trifluoro-2-[(4-fluoroanilino)methylidene]-1-(2-thienyl)butane-1,3-dione (CAS 332055-70-6)
- Moxifloxacin Impurity 44 (CAS 112811-70-8)
- 2-(4-Methoxyphenyl)-2-(3-(trifluoromethyl)quinoxalin-2-yl)acetonitrile (CAS 477867-64-4)
- Riociguat Impurity 31 (CAS CATO-C4X-174931)
- 1-(2-(Phenylethynyl)phenyl)ethanone (CAS 171258-08-5)
- 4-Bromo-2-iodo-5-(trifluoromethyl)pyridine (CAS 1227571-68-7)
- 1-(4-Chlorobenzyl)-3'-phenylspiro[indoline-3,2'-thiazolidine]-2,4'-dione (CAS 338419-04-8)
- (6-(Benzyloxy)-2,5,7,8-tetramethylchroman-2-yl)methanol (CAS 171270-07-8)
- 1-(3-Bromo-4-methoxyphenyl)ethan-1-ol (CAS 94670-25-4)
- Relugolix Impurity 61 (CAS CATO-C4X-242961)
- 1-(4-Bromophenyl)cyclopentanecarboxylic Acid (CAS 143328-24-9)
- Ethyl 6-Bromo-5-methoxyindole-2-carboxylate (CAS 128593-40-8)
- 4-(Benzyloxy)-5-bromo-2-chloropyrimidine (CAS 205672-19-1)
- D-Pro38-Tirzepatide (CAS CATO-CPTD788901)
Why CATO?
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