N-(5-Oxo-1-(2,2,2-trifluoroethyl)-4,5-dihydro-1H-pyrazol-3-yl)methacrylamide CAS 29572-45-0
| CAS No. | 29572-45-0 |
| Molecular Formula | C9H10F3N3O2 |
| Molecular Weight | 249.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
N-(5-Oxo-1-(2,2,2-trifluoroethyl)-4,5-dihydro-1H-pyrazol-3-yl)methacrylamide (CAS 29572-45-0), molecular formula C9H10F3N3O2 and molecular weight 249.19 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, N-(5-Oxo-1-(2,2,2-trifluoroethyl)-4,5-dihydro-1H-pyrazol-3-yl)methacrylamide is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 249.19 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H10F3N3O2 |
| Molecular Weight | 249.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Recommended Standards
- n-(3,4-Dihydroxyphenethyl)-2,2,2-trifluoroacetamide (CAS 65846-04-0)
- n-Methoxy-n-methyl-4-(trifluoromethoxy)benzamide (CAS 897656-36-9)
- Methyl 5-amino-2-methoxy-4-(trifluoromethyl)benzoate (CAS 885518-37-6)
- rac-(5R,7R)-5-methyl-7-(trifluoromethyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (CAS 2059917-72-3)
- tert-Butyl (5-amino-3-methylpyridin-2-yl)(tert-butoxycarbonyl)carbamate (CAS 1393553-87-1)
- (S)-5-Amino-5-oxo-2-(2,2,2-trifluoroacetamido)pentanoic acid (CAS 2419-34-3)
- 9-trans-12-Hydroxyoctadecenoic acid (CAS 540-12-5)
- 1-Benzyl-3,5-dimethyl-1H-pyrazol-4-amine (CAS 28466-69-5)
- Solanin D (CAS 474-08-8)
- Methyl 5-cyclopropyl-4-iodo-1-methyl-1H-pyrazole-3-carboxylate (CAS 1247527-40-7)
- Lenvatinib Impurity 149 (CAS CATO-C4X-1140149)
- 1-(2-(4-Chlorophenyl)-2-oxoethyl)pyridin-2(1H)-one (CAS 108664-55-7)
- tert-Butyl 3-(aminomethyl)-1-oxa-7-azaspiro[4.5]decane-7-carboxylate (CAS 1160247-18-6)
- [His]1+12-Semaglutide (CAS CATO-C4X-2226178)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com