Fmoc-(2S,3S)-3-hydroxypyrrolidine-2-carboxylic acid CAS 296774-32-8
| CAS No. | 296774-32-8 |
| Molecular Formula | C20H19NO5 |
| Molecular Weight | 353.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Fmoc-(2S,3S)-3-hydroxypyrrolidine-2-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Fmoc-(2S,3S)-3-hydroxypyrrolidine-2-carboxylic acid (CAS 296774-32-8), a certified reference material (molecular formula C20H19NO5, MW 353.37 g/mol) for analytical method development and quality control.
The molecular framework of Fmoc-(2S,3S)-3-hydroxypyrrolidine-2-carboxylic acid (C20H19NO5) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C20H19NO5 |
| Molecular Weight | 353.37 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 1 |
Related Fmoc Standards
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- 4-Fmoc-morpholine-3-carboxylic Acid (CAS 204320-51-4)
- Fmoc-Cop (CAS 312965-04-1)
- Fmoc-D-cis-Hyp-OH (CAS 214852-45-6)
- Fmoc-tBu-D-Gly-OH (CAS 198543-64-5)
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Recommended Standards
- (2R,3R,4S)-2,3,4,5-Tetrahydroxy-3-(hydroxymethyl)pentanal (CAS 99247-35-5)
- (5BS,6R,12bR)-13-methyl-5b,6,7,12b,13,14-hexahydro-[1,3]dioxolo[4',5':4,5]benzo[1,2-c][1,3]dioxolo[4,5-i]phenanthridin-6-ol (CAS 88200-01-5)
- (1S,3s)-1-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-hydroxycyclobutane-1-carboxylic acid (CAS 2137143-57-6)
- (R)-LY341495 (CAS 201851-15-2)
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(3-((2,4-dichlorobenzyl)oxy)thiophen-2-yl)hydrazine-1-carboxamide (CAS 303147-96-8)
- Tilianin (CAS 4291-60-5)
- 3,3,6,6-Tetramethyl-1,4-dioxane-2,5-dione (CAS 6713-72-0)
- Caffeic Acid 4-Sulfate (CAS 151481-51-5)
- (1-(Methylsulfonyl)cyclohexyl)methanamine (CAS 1251305-93-7)
- Tert-butyl 2-(hydroxymethyl)-4-((tetrahydro-2H-pyran-2-yl)oxy)pyrrolidine-1-carboxylate (CAS 1822565-28-5)
- 2-Fluoro-4-isocyanatobenzonitrile (CAS 1261606-20-5)
- Efinaconazole Impurity 39 (CAS 2122222-10-8)
- (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-(3-hydroxyphenyl)acetic acid (CAS 615553-60-1)
- Semaglutide impurity 78 (CAS CATO-C4X-222678)
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