3-((4-Hydroxy-3-(piperidin-1-ylmethyl)phenyl)amino)benzo[d]isothiazole 1,1-dioxide CAS 296791-77-0
| CAS No. | 296791-77-0 |
| Molecular Formula | C19H21N3O3S |
| Molecular Weight | 371.45 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-((4-Hydroxy-3-(piperidin-1-ylmethyl)phenyl)amino)benzo[d]isothiazole 1,1-dioxide (CAS 296791-77-0) is a high-purity analytical reference standard with the molecular formula C19H21N3O3S and a molecular weight of 371.45 g/mol.
Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, 3-((4-Hydroxy-3-(piperidin-1-ylmethyl)phenyl)amino)benzo[d]isothiazole 1,1-dioxide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 371.45 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H21N3O3S |
| Molecular Weight | 371.45 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- 4-Amino-2-(difluoromethyl)-6-hydroxypyridine-3-sulfonyl chloride (CAS 1805330-81-7)
- 7-[1-(2,6-Dimethylphenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine (CAS 477865-17-1)
- (3-Isopropyl-1,2,4-oxadiazol-5-yl)methanamine (CAS 936940-67-9)
- 5-(2-Methoxybenzyl)oxazolidin-2-one (CAS 62826-01-1)
- 2-(5-Methyl-2-furyl)quinoline-4-carbonyl chloride (CAS 1160264-92-5)
- 4-(1-(tert-Butoxycarbonyl)piperidin-4-yl)-2-methylbenzoic acid (CAS 2270905-31-0)
- 3-Pentyl isothiocyanate (CAS 201224-89-7)
- (R)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-2-(2,4-dimethoxybenzyl)propanoic acid (CAS 1260614-12-7)
- 2,4,5,6-Tetrahydro-3-cyclopentapyrazolecarboxylic acid (CAS 884497-47-6)
- Semaglutide impurity 257 (CAS CATO-C4X-2226257)
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