6-Chloro-3-(1,1,2,2,3,3,3-heptafluoropropyl)-[1,2,4]triazolo[4,3-b]pyridazine CAS 296898-46-9
| CAS No. | 296898-46-9 |
| Molecular Formula | C8H2ClF7N4 |
| Molecular Weight | 322.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Chloro-3-(1,1,2,2,3,3,3-heptafluoropropyl)-[1,2,4]triazolo[4,3-b]pyridazine.
6-Chloro-3-(1,1,2,2,3,3,3-heptafluoropropyl)-[1,2,4]triazolo[4,3-b]pyridazine (CAS 296898-46-9), molecular formula C8H2ClF7N4 and molecular weight 322.57 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 6-Chloro-3-(1,1,2,2,3,3,3-heptafluoropropyl)-[1,2,4]triazolo[4,3-b]pyridazine (C8H2ClF7N4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 6-Chloro-3-(1,1,2,2,3,3,3-heptafluoropropyl)-[1,2,4]triazolo[4,3-b]pyridazine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H2ClF7N4 |
| Molecular Weight | 322.57 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
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Recommended Standards
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- 2-Bromo-N-(5-chloro-2,4-dimethoxyphenyl)propanamide (CAS 1119452-45-7)
- 4,4′-Methylenebis(2,6-diethylaniline) (CAS 13680-35-8)
- 2,6-Dichloro-4-fluorophenylacetonitrile (CAS 1803854-81-0)
- N-cyclohexylmorpholine-4-carboxamide (CAS 3417-54-7)
- N-(4-mercaptophenyl)cyclopropanecarboxamide (CAS 639090-54-3)
- 2-Bromo-N-(3-cyano-6-methyl-4,5,6,7-tetrahydro-1-benzothien-2-yl)butanamide (CAS 1284156-83-7)
- Dibromochloroacetonitrile (CAS 144772-39-4)
- 5-Chloro-3-fluoro-2-vinylpyridine (CAS 1374652-70-6)
- N-((Tetrahydrofuran-2-yl)methyl)-6-(trifluoromethoxy)benzo[d]thiazol-2-amine (CAS 1251544-50-9)
- 4-(2-Methyl-1H-imidazol-1-yl)butanoic acidhydrochloride (CAS 1094607-15-4)
- Ethyl 2-(4-(1,3-dioxan-2-yl)phenyl)-2-oxoacetate (CAS 951888-34-9)
- Semaglutide impurity 66 (CAS CATO-C4X-222666)
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