(E)-N-(4-chlorobenzyl)-3-(4-ethoxyphenyl)acrylamide CAS 297149-87-2
| CAS No. | 297149-87-2 |
| Molecular Formula | C18H18ClNO2 |
| Molecular Weight | 315.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (E)-N-(4-chlorobenzyl)-3-(4-ethoxyphenyl)acrylamide is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies (E)-N-(4-chlorobenzyl)-3-(4-ethoxyphenyl)acrylamide (CAS 297149-87-2), a certified reference material (molecular formula C18H18ClNO2, MW 315.79 g/mol) for analytical method development and quality control.
The molecular framework of (E)-N-(4-chlorobenzyl)-3-(4-ethoxyphenyl)acrylamide (C18H18ClNO2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (E)-N-(4-chlorobenzyl)-3-(4-ethoxyphenyl)acrylamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H18ClNO2 |
| Molecular Weight | 315.79 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- (E)-[(4-Chlorophenyl)methylidene]amino 4-tert-butylbenzoate (CAS 331462-08-9)
- 1-Benzyl-4-(2-chlorophenyl)pyrrolidine-3-carboxylic acid (CAS 939757-57-0)
- (4-Chlorophenyl)[4-(4-piperidinyloxy)phenyl]-methanone (CAS 946714-89-2)
- 1-Benzyl-4-(3-chlorophenyl)pyrrolidine-3-carboxylic acid hydrochloride (CAS 874990-63-3)
- 2-(Isoquinolin-5-yl)-2-methylpropanoic acid (CAS 581813-24-3)
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- N-(3-chloro-4-fluorophenyl)-2-((furan-2-ylmethyl)amino)-2-thioxoacetamide (CAS 329078-84-4)
- 2-(4-Methoxyphenoxy)-5-nitrobenzoic acid (CAS 33459-12-0)
- Methyl 4-nitro-2-(trifluoromethyl)benzoate (CAS 900254-47-9)
- 4-Amino-N-(3,5-dimethylphenyl)benzenesulfonamide (CAS 874212-15-4)
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- 3-(((3,5-Dimethylpiperidin-1-yl)sulfonyl)methyl)aniline (CAS 1094892-69-9)
- 2-[(2-hydroxyethyl)sulfanyl]benzoic acid (CAS 58980-52-2)
- Peptide Impurity 28 (CAS 1350456-64-2)
Why CATO?
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