1-[2-(benzyloxy)-5-fluorophenyl]-2-bromo-3-[4-(trifluoromethyl)phenyl]propan-1-one CAS 298186-76-2
| CAS No. | 298186-76-2 |
| Molecular Formula | C23H17BrF4O2 |
| Molecular Weight | 481.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-[2-(benzyloxy)-5-fluorophenyl]-2-bromo-3-[4-(trifluoromethyl)phenyl]propan-1-one is closely related to a steroid core, a hydroxyl group, an ether linkage, fluorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 1-[2-(benzyloxy)-5-fluorophenyl]-2-bromo-3-[4-(trifluoromethyl)phenyl]propan-1-one (CAS 298186-76-2), a certified reference material (molecular formula C23H17BrF4O2, MW 481.28 g/mol) for analytical method development and quality control.
1-[2-(benzyloxy)-5-fluorophenyl]-2-bromo-3-[4-(trifluoromethyl)phenyl]propan-1-one (C23H17BrF4O2) contains a steroid core, a hydroxyl group, an ether linkage, fluorine/bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-[2-(benzyloxy)-5-fluorophenyl]-2-bromo-3-[4-(trifluoromethyl)phenyl]propan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H17BrF4O2 |
| Molecular Weight | 481.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Br-containing |
Related benzyloxy Standards
- 1-(4-(Benzyloxy)phenyl)propan-2-one (CAS 5586-92-5)
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- 3-(2-(Benzyloxy)-5-bromophenyl)-N,N-diisopropyl-3-phenylpropan-1-amine (CAS 156755-27-0)
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- 2-{N-[5-(benzyloxy)-2,4-dichlorophenyl]4-methylbenzenesulfonamido}acetic acid (CAS 338961-73-2)
- 2-(3-(4-(Benzyloxy)-3-methoxyphenyl)-2-bromoacrylamido)benzoic acid (CAS 1252992-36-1)
- 2,6-Bis(benzyloxy)-3-(4-bromo-2,6-difluorophenyl)pyridine (CAS 2758532-18-0)
- Ethyl 3-(4-(benzyloxy)-3,5-dimethoxyphenyl)-3-hydroxy-2-(2-methoxyphenoxy)propanoate (CAS 151541-15-0)
Recommended Standards
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- 5,5'-((1E,1'E)-(2-Bromo-1,4-phenylene)bis(Ethene-2,1-Diyl))bis(2-hydroxyBenzoic acid) (CAS 291766-06-8)
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- N-(2-chloro-5-nitrophenyl)acetamide (CAS 4031-81-6)
- 3-Fluoro-2-iodobenzonitrile (CAS 916792-62-6)
- 4'-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-[1,1'-biphenyl]-4-carbaldehyde (CAS 1040424-52-9)
- 3-Chloro-6-iodopyrazine-2-carbonitrile (CAS 1392149-80-2)
- benzyl (3S,4S)-4-azido-3-hydroxy-piperidine-1-carboxylate (CAS 2382469-24-9)
- 4-Amino-N-cyclohexylbenzamide (CAS 17675-42-2)
- Semaglutide impurity 276 (CAS CATO-C4X-2226276)
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