2-[4-(Trifluoromethyl)phenyl]pyrrolidine CAS 298690-84-3
| CAS No. | 298690-84-3 |
| Molecular Formula | C11H12F3N |
| Molecular Weight | 215.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-[4-(Trifluoromethyl)phenyl]pyrrolidine (CAS 298690-84-3), molecular formula C11H12F3N and molecular weight 215.21 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution, 2-[4-(Trifluoromethyl)phenyl]pyrrolidine is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 215.21 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-[4-(Trifluoromethyl)phenyl]pyrrolidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H12F3N |
| Molecular Weight | 215.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluoromethyl Standards
- 3-(4-(Trifluoromethyl)phenyl)pyrrolidine (CAS 1000198-76-4)
- 2-(3-(Trifluoromethyl)phenyl)pyrrolidine (CAS 109086-17-1)
- 1-[3-(Trifluoromethyl)phenyl]cyclobutanamine (CAS 1094218-35-5)
- 1-(4-(Trifluoromethyl)phenyl)pyrrolidine (CAS 113845-68-4)
- (S)-6-(Trifluoromethyl)-1,2,3,4-tetrahydronaphthalen-1-amine (CAS 1212870-73-9)
- (R)-7-(trifluoromethyl)-1,2,3,4-tetrahydronaphthalen-1-amine (CAS 1213949-23-5)
- (S)-2-(2-(Trifluoromethyl)phenyl)pyrrolidine (CAS 1217710-14-9)
- (S)-2-(3-(Trifluoromethyl)phenyl)pyrrolidine (CAS 1217777-12-2)
Recommended Standards
- 2-[(pyridin-3-yl)amino]pyridine-3-carboxylic acid (CAS 68671-71-6)
- 2-Amino-4-phenylpyrimidine-5-carboxylic acid (CAS 91093-42-4)
- 2-[(2,5-dioxoimidazolidin-1-yl)methyl]benzonitrile (CAS 923191-32-6)
- 2-Amino-5-(5-pyrimidinyl)benzoic acid (CAS 889949-97-7)
- 3,3,3-Trifluoro-N-(piperidin-3-ylmethyl)propanamide (CAS 1016726-48-9)
- N-((1-methyl-5-phenoxy-3-(trifluoromethyl)-1H-pyrazol-4-yl)methyl)pivalamide (CAS 956754-22-6)
- tert-Butyl 3-formyl-1H-pyrrolo[2,3-β]pyridine-1-carboxylate (CAS 144657-66-9)
- 2-(Difluoromethoxy)naphthalene-5-methanol (CAS 1261844-33-0)
- N-(4-Cyano-3-cyclopropoxypyridin-2-yl)methanesulfonamide (CAS 1243389-30-1)
- 4,4,5,5-Tetramethyl-2-(oxetan-3-ylidenemethyl)-1,3,2-dioxaborolane (CAS 2246658-69-3)
- N-(4-Ethoxyphenyl)-2-methylquinazolin-4-amine (CAS 610255-68-0)
- 1,8-Dioxa-4-azaspiro[5.5]undecane (CAS 1226975-76-3)
- 2-[2-(Hydroxymethyl)-1H-pyrrol-1-yl]-4-methoxypyridine-3-carbonitrile (CAS 338411-81-7)
- Semaglutide impurity 237 (CAS CATO-C4X-2226237)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com