S-Adenosyl-L-Methionine CAS 29908-03-0
| CAS No. | 29908-03-0 |
| Molecular Formula | C15H22N6O5S |
| Molecular Weight | 398.44 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
S-Adenosyl-L-Methionine (CAS 29908-03-0) is a high-purity analytical reference standard with the molecular formula C15H22N6O5S and a molecular weight of 398.44 g/mol.
The molecular framework of S-Adenosyl-L-Methionine (C15H22N6O5S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), S-Adenosyl-L-Methionine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H22N6O5S |
| Molecular Weight | 398.44 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 1 |
Related S Standards
- S-Adenosyl-D-methionine (CAS 14031-35-7)
- S-Adenosyl-L-Methionine-d3 (CAS CATO-C4X-138122)
- S-(5'-Adenosyl)-L-homocysteine (CAS 979-92-0)
- Adenosyl Methionine Impurity 8 (CAS 59987-48-3)
- S-Adenosyl-L-Methionine Impurity 19 (CAS 13484-65-6)
- S-Adenosyl-L-Methionine Impurity 13 (CAS CATO-C4X-138113)
- S-Adenosyl-L-Methionine Impurity 14 (CAS CATO-C4X-138114)
- S-Adenosyl-L-Methionine Impurity 10 (CAS 4229-50-9)
Recommended Standards
- N-{4-[(2,6-Dimethylpyrimidin-4-yl)sulfamoyl]phenyl}-3-(furan-2-yl)prop-2-enamide (CAS 518350-19-1)
- Ticagrelor Impurity 93 (CAS CATO-C4X-109393)
- N-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2-((4-ethyl-5-(pyrazin-2-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 618427-26-2)
- Ilaprazole impurity 189 (CAS CATO-C4X-1130189)
- Tris(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)amine (CAS 267221-90-9)
- 3-Azetidinomethyl-2,5-dichlorobenzophenone (CAS 898772-12-8)
- Amines, N-coco alkyltrimethylenedi- (CAS 61791-63-7)
- Ethyl 2-(2,2,2-trifluoroethoxy)acetate (CAS 88383-15-7)
- methyl N-[2-chloro-4-(chlorosulfonyl)phenyl]carbamate (CAS 1599787-03-7)
- tert-Butyl 6-bromo-4-fluoro-1H-indole-1-carboxylate (CAS 1799412-27-3)
- Dimethyl 2-(4-nitrophenyl)-2-propylmalonate (CAS 685108-29-6)
- 3-amino-4-(ethylamino)-N,N-dimethylbenzenesulfonamide (CAS 735322-65-3)
- 4,6-Dimethyl-2-((piperidin-4-ylmethyl)thio)pyrimidine hydrochloride (CAS 1420904-11-5)
- Semaglutide Impurity 188 (CAS CATO-C4X-2226188)
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