1-(2-Chloro-5-(trifluoromethyl)phenyl)-1H-pyrrole-2-carbaldehyde CAS 299165-51-8
| CAS No. | 299165-51-8 |
| Molecular Formula | C12H7ClF3NO |
| Molecular Weight | 273.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(2-Chloro-5-(trifluoromethyl)phenyl)-1H-pyrrole-2-carbaldehyde (CAS 299165-51-8) is a high-purity analytical reference standard with the molecular formula C12H7ClF3NO and a molecular weight of 273.64 g/mol.
Structurally, 1-(2-Chloro-5-(trifluoromethyl)phenyl)-1H-pyrrole-2-carbaldehyde (C12H7ClF3NO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 273.64 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H7ClF3NO |
| Molecular Weight | 273.64 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 2-Chloro-N-[4-(trifluoromethyl)-phenyl]pyrimidin-4-amine (CAS 1036705-78-8)
- 6-Chloro-N-[3-(trifluoromethyl)phenyl]pyridazin-3-amine (CAS 1097067-82-7)
- 8-chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine-3-carboxylic acid (CAS 1211803-76-7)
- 7-Chloro-2-ethyl-5-(trifluoromethyl)-1H-pyrrolo[3,2-b]pyridine-6-carbonitrile (CAS 1260897-26-4)
- 2-chloro-4-[3-(trifluoromethoxy)phenyl]pyridine (CAS 1261856-64-7)
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- 1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-oxocyclobutanecarbonitrile (CAS 1432048-96-8)
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Recommended Standards
- 3-Chloro-2-(3-(trifluoromethyl)phenoxy)pyridine (CAS 197565-66-5)
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- 1-(2-Chloro-7-(trifluoromethyl)quinolin-3-yl)ethanone (CAS 1956379-04-6)
- 2-Chloro-4-(4-trifluoromethoxyphenyl)pyridine (CAS 697739-19-8)
- alpha-Glycerol Phosphate Calcium Salt (CAS 398143-83-4)
- 2-Bromo-N-(2-hydroxyphenyl)benzamide (CAS 54255-52-6)
- N-Hydroxy-3-(3H-imidazo[4,5-b]pyridin-2-yl)benzimidamide (CAS 1256486-26-6)
- 4-Bromo-1-ethyl-1h-indole-2-carboxylic acid (CAS 1240567-83-2)
- 1-Vinyl-1H-pyrrole-2,5-dione (CAS 7685-94-1)
- 3-(((5-Methylfuran-2-yl)methyl)amino)tetrahydrothiophene 1,1-dioxide (CAS 914207-45-7)
- 5-(1-Isobutylpyrrolidin-2-yl)-2-methoxy-3-methylpyridine (CAS 1352534-44-1)
- 4-{6-[(2-Pyridinylmethyl)amino]-1H-pyrrolo[2,3-b]pyridin-4-yl}benzoic acid (CAS 1377872-06-4)
- Dimethyl 1-(p-tolyl)-1H-1,2,3-triazole-4,5-dicarboxylate (CAS 166031-15-8)
- 263251-78-1 NMG938VJ6T D-3 Tavilermide [USAN:INN] UNII-NMG938VJ6T MIM-D3 MIM-D 3 D 3 (peptide) Tavilermide (CAS 263251-78-1)
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