2-Amino-2-(2,4-dichlorophenyl)acetic Acid CAS 299169-13-4
| CAS No. | 299169-13-4 |
| Molecular Formula | C8H7Cl2NO2 |
| Molecular Weight | 220.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-Amino-2-(2,4-dichlorophenyl)acetic Acid (CAS 299169-13-4), molecular formula C8H7Cl2NO2 and molecular weight 220.05 g/mol, is a CATO reference standard with documented purity and traceability.
2-Amino-2-(2,4-dichlorophenyl)acetic Acid (C8H7Cl2NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H7Cl2NO2 |
| Molecular Weight | 220.05 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Amino Standards
- (S)-2-Amino-2-(3,4-dichlorophenyl)acetic acid (CAS 1241677-98-4)
- (R)-2-Amino-2-(3,4-dichlorophenyl)acetic acid (CAS 1241683-83-9)
- 6-Amino-2,4-dichloro-3-methylbenzoic acid (CAS 1250217-47-0)
- Methyl 3-amino-4,5-dichlorobenzoate (CAS 1250663-38-7)
- 2-Amino-2-(3,4-dichlorophenyl)acetic Acid (CAS 128349-50-8)
- Methyl 3-amino-2,6-dichlorobenzoate (CAS 1340366-65-5)
- Methyl 5-amino-2,3-dichlorobenzoate (CAS 1343702-03-3)
- Methyl 4-amino-2,5-dichlorobenzoate (CAS 1449239-00-2)
Recommended Standards
- 2,6-Dichloro-4-ethylnicotinic acid (CAS 62774-91-8)
- 2-Amino-2-(2,5-dichlorophenyl)acetic Acid (CAS 500695-97-6)
- 2,5-Dimethylbenzylzinc chloride (CAS 737797-24-9)
- 2-amino-2-(2,6-dichlorophenyl)acetic acid (CAS 42057-30-7)
- (S)-2-(2-Fluoro-[1,1'-biphenyl]-4-yl)pyrrolidine (CAS 1389819-62-8)
- 4-Ethyl-2(1H)-quinolinone (CAS 61304-66-3)
- 7-(4-Chlorophenoxy)-3-phenyl-2,3-dihydro-1H-inden-1-one (CAS 339115-91-2)
- 3-Amino-5-fluoropicolinamide (CAS 1804146-01-7)
- 4-Hydroxy-1,2,2,6,6-pentamethylpiperidine (CAS 2403-89-6)
- 2-((2-Hydroxyquinolin-8-yl)oxy)propanoic acid (CAS 1225751-57-4)
- (1-(3-Fluorophenyl)-1H-pyrazol-4-yl)methanamine hydrochloride (CAS 1390655-01-2)
- Tert-butyl (3R,4S)-4-(4-fluorophenyl)-3-(hydroxymethyl)piperidine-1-carboxylate (CAS 179179-79-4)
- 2,4-Diaminopyrimidine-5-carboxamide (CAS 66131-74-6)
- Tau Peptide (275-305) (Repeat 2 Domain) trifluoroacetate salt (CAS 330456-25-2)
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