3-Chloro-5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid CAS 299405-80-4
| CAS No. | 299405-80-4 |
| Molecular Formula | C14H7ClF3N3O2 |
| Molecular Weight | 341.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 341.67 g/mol gives 3-Chloro-5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3-Chloro-5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid (CAS 299405-80-4), molecular formula C14H7ClF3N3O2 and molecular weight 341.67 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 3-Chloro-5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 341.67 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3-Chloro-5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H7ClF3N3O2 |
| Molecular Weight | 341.67 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 3-(4-(4-Chloro-2-(trifluoromethyl)phenyl)pyridin-2-yl)-1,2,4-oxadiazol-5(4H)-one (CAS 1219454-01-9)
- methyl 5-chloro-2-methoxy-4-{[(2,2,2-trifluoroethoxy)carbonyl]amino}benzoate (CAS 1223395-43-4)
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-2-(4-nitrophenyl)acetonitrile (CAS 213994-29-7)
- 2-[8-Chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]benzoic acid (CAS 672951-21-2)
- 2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,3-dihydro-1H-isoindole-1,3-dione (CAS 338770-62-0)
- 2-Chloro-4-{5-[2-(trifluoromethoxy)phenyl]-1,3,4-oxadiazol-2-yl}pyridine (CAS 680216-51-7)
- 3-Chloro-2-[2-(1,3,4-oxadiazol-2-yl)phenoxy]-5-(trifluoromethyl)pyridine (CAS 303148-24-5)
- 8-Chloro-2-(3-nitrophenyl)-6-(trifluoromethyl)imidazo[1,2-a]pyridine (CAS 860651-00-9)
Recommended Standards
- 5-(4-Methoxy-phenylamino)-[1,3,4]thiadiazole-2-thiol (CAS 37844-24-9)
- 1-(4-Chloro-3-nitrophenyl)-3-(ethoxycarbonyl)-4,5-dihydro-1h-pyrazole-5-carboxylic acid (CAS 1264040-52-9)
- 1-(2-Chloro-5-nitrophenyl)-3-(ethoxycarbonyl)-4,5-dihydro-1h-pyrazole-5-carboxylic acid (CAS 1264044-32-7)
- 2-(4-Chlorophenyl)-5-nitro-3-(trifluoromethyl)benzofuran (CAS 821770-05-2)
- 2-(2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide (CAS 1218789-98-0)
- 3-[6-(1-Acetyl-piperidin-4-yl)-2-methyl-pyrimidin-4-yl]-propionic acid (CAS 1316217-62-5)
- 2-Methyl-benzooxazole-6-carbonyl chloride (CAS 202195-57-1)
- 2,2'-((1E,1'E)-(((1S,2S)-1,2-Diphenylethane-1,2-diyl)bis(azanylylidene))bis(methanylylidene))diphenol (CAS 177770-03-5)
- N-Fmoc-4-(methylamino)benzoic acid (CAS 160977-92-4)
- 2-Chloro-3-ethoxy-5-nitropyridine (CAS 1352910-89-4)
- 2-Bromo-7-chloroquinoline (CAS 1044764-18-2)
- 6-((3-Iodoprop-2-yn-1-yl)thio)-2-(methylthio)pyrimidin-4(1H)-one (CAS 111787-42-9)
- 1-Methyl-N-(3-methylbenzyl)pyrrolidin-3-amine (CAS 1249021-81-5)
- [α-Glu](Side Chain)-Semaglutide (CAS CATO-C4X-2226159)
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