Etoricoxib impurity 69 CAS 300355-18-4
| CAS No. | 300355-18-4 |
| Molecular Formula | C10H12O4S |
| Molecular Weight | 228.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Etoricoxib impurity 69 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Etoricoxib impurity 69 (CAS 300355-18-4, C10H12O4S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system, Etoricoxib impurity 69 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 228.26 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C10H12O4S |
| Molecular Weight | 228.26 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Sulfur Atoms | 1 |
Related Etoricoxib Standards
- Etoricoxib Impurity 3 (CAS 90584-68-2)
- EtoricoxiB impurity 16 (CAS 90536-66-6)
- Etoricoxib impurity 68 (CAS 58058-86-9)
- Etoricoxib Impurity 75 (CAS 40061-49-2)
- Etoricoxib Impurity 77 (CAS CATO-C4X-108077)
- Etoricoxib Impurity 71 (CAS 887479-63-2)
- Etoricoxib Impurity 88 (CAS CATO-C4X-108088)
- Etoricoxib Impurity 31 (CAS 93629-02-8)
Recommended Standards
- 2-Methoxy-1-(4-(methylsulfonyl)phenyl)ethan-1-one (CAS 1596988-99-6)
- Ibuprofen EP Impurity B Sodium (CAS CATO-C4X-108236)
- 70987-78-9 (S)-Glycidyl tosylate Oxiranemethanol, 4-methylbenzenesulfonate, (S)- Oxiranemethanol, 4-methylbenzene-sulfonate, (S)- 5-17-03-00047 (Beilstein Handbook Reference) BRN 3592143 CCRIS 6400 (+)-Glycidyl tosylate (2S)-(+)-Glycidyl tosylate EC 417-210-7 (CAS 70987-78-9)
- 4-(4-Methylthiazole-5-carboxamido)butanoic acid (CAS 1016672-70-0)
- Fasudil Impurity 26 (CAS 4392-52-3)
- Ezetimibe Impurity 141 (CAS CATO-C4X-1098141)
- Nifuratel Impurity 19 (CAS CATO-C4X-127219)
- 1-(Cyclopentylamino)propan-2-ol (CAS 878889-25-9)
- (2-Chloro-4-cyclopropyl-6-methylphenyl)boronic acid (CAS 2225173-13-5)
- 5-Fluoro-2-methyl-6-(perfluoroethyl)pyrimidin-4(3H)-one (CAS 1548-79-4)
- 2-(3-Carboxypropanoyl)benzoic acid (CAS 27415-09-4)
- 1,1-Dimethoxy-N,N-dimethylpropan-2-amine (CAS 1246225-38-6)
- tert-Butyl (R)-9-oxooctahydro-2H-pyrazino[1,2-a]pyrazine-2-carboxylate (CAS 2924021-45-2)
- Acetyl Tetrapeptide-11 (CAS 928006-88-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com