N-(4-morpholinophenyl)-2,4-dinitroaniline CAS 300375-20-6

Purity 97%+In StockPharmaceutical Standards
CAS No.300375-20-6
Molecular FormulaC16H16N4O5
Molecular Weight344.32 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-(4-morpholinophenyl)-2,4-dinitroaniline CAS 300375-20-6 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-(4-morpholinophenyl)-2,4-dinitroaniline.

N-(4-morpholinophenyl)-2,4-dinitroaniline (CAS 300375-20-6) is a high-purity analytical reference standard with the molecular formula C16H16N4O5 and a molecular weight of 344.32 g/mol.

The molecular framework of N-(4-morpholinophenyl)-2,4-dinitroaniline (C16H16N4O5) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), N-(4-morpholinophenyl)-2,4-dinitroaniline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC16H16N4O5
Molecular Weight344.32 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Nitrogen Atoms4

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