1-Cyclopropyl-5-methoxy-2-methyl-1h-indole-3-carboxylic acid CAS 300541-60-0
| CAS No. | 300541-60-0 |
| Molecular Formula | C14H15NO3 |
| Molecular Weight | 245.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-Cyclopropyl-5-methoxy-2-methyl-1h-indole-3-carboxylic acid (CAS 300541-60-0) is a high-purity analytical reference standard with the molecular formula C14H15NO3 and a molecular weight of 245.27 g/mol.
1-Cyclopropyl-5-methoxy-2-methyl-1h-indole-3-carboxylic acid (C14H15NO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-Cyclopropyl-5-methoxy-2-methyl-1h-indole-3-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H15NO3 |
| Molecular Weight | 245.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 1 |
Related Cyclopropyl Standards
- 1-Cyclopropyl-5-oxo-2-phenyl-3-pyrrolidinecarboxylic acid (CAS 1219571-56-8)
- Methyl 1-cyclopropyl-5-hydroxy-2-methyl-1h-indole-3-carboxylate (CAS 879362-72-8)
- Methyl 6-cyclopropyl-1-ethyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate (CAS 1018125-75-1)
- 7-Cyclopropyl-2-isopropylpyrazolo[1,5-a]pyrimidine-5-carboxylic acid (CAS 1226104-81-9)
- 6-cyclopropyl-3-(propan-2-yl)-[1,2]oxazolo[5,4-b]pyridine-4-carboxamide (CAS 1354963-26-0)
- 4-(3-Cyclopropyl-1H-1,2,4-triazol-5-yl)-2-ethoxyphenol (CAS 1416347-21-1)
- N-Cyclopropyl-2-(3-oxo-1,2,3,4-tetrahydroquinoxalin-2-yl)acetamide (CAS 1428139-01-8)
- 1-(4-Cyclopropyl-6-(cyclopropylamino)-1,3,5-triazin-2-yl)azetidin-3-one (CAS 148312-49-6)
Recommended Standards
- 1-Boc-4-hydroxypiperidine-4-carboxylic Acid (CAS 495414-64-7)
- 1-tert-butyl 2-methyl (2R,3R)-3-hydroxypyrrolidine-1,2-dicarboxylate (CAS 2165775-01-7)
- 1-Boc-3-Formylindole (CAS 57476-50-3)
- 1-tert-Butyl 3-methyl 3-hydroxypyrrolidine-1,3-dicarboxylate (CAS 942190-61-6)
- tert-Butyl (cis-4-(aminomethyl)cyclohexyl)carbamate (CAS 509143-00-4)
- 3-[(2-Chlorophenyl)methyl]-8-fluoro-3H,4H,5H-pyrimido[5,4-b]indol-4-one (CAS 1031557-91-1)
- Ethyl 3-Cyclopropylpyrrole-2-carboxylate (CAS 1123725-69-8)
- tert-Butyl 6-cyano-5-fluoronicotinate (CAS 2167666-52-4)
- 3-Tert-butyl-5-chloro-1,2,4-thiadiazole (CAS 57370-16-8)
- 4-{[(furan-2-ylmethyl)amino](phenyl)methyl}phenol hydrochloride (CAS 1208889-22-8)
- N-(2-Methylnaphthalen-1-yl)acetamide (CAS 13615-35-5)
- 2-(1-(2-Methoxy-2-oxoethyl)cyclopropyl)acetic acid (CAS 1554535-00-0)
- N-(4-(N-(naphthalen-1-yl)sulfamoyl)phenyl)acetamide (CAS 56799-96-3)
- Palmitoyl Hexapeptide-12 (CAS 171263-26-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com