6-Amino-4-(4-methoxyphenyl)-3-methyl-1-(p-tolyl)-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile CAS 300701-99-9
| CAS No. | 300701-99-9 |
| Molecular Formula | C22H20N4O2 |
| Molecular Weight | 372.42 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies 6-Amino-4-(4-methoxyphenyl)-3-methyl-1-(p-tolyl)-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile (CAS 300701-99-9), a certified reference material (molecular formula C22H20N4O2, MW 372.42 g/mol) for analytical method development and quality control.
6-Amino-4-(4-methoxyphenyl)-3-methyl-1-(p-tolyl)-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile (C22H20N4O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C22H20N4O2 |
| Molecular Weight | 372.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 4 |
Related Amino Standards
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- 2-Amino-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-8-(p-tolylamino)-1H-purin-6(9H)-one (CAS 126788-73-6)
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Recommended Standards
- 6,6'-(Ethane-1,2-diyl)bis(3-aminobenzenesulfonic acid) (CAS 5136-34-5)
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- 5-(4-Benzoylpiperazin-1-yl)-2-(p-tolyl)oxazole-4-carbonitrile (CAS 946308-06-1)
- Argatroban Impurity N2 (CAS 79672-38-1)
- 3-Fluoro-2-hydrazinyl-5-(trifluoromethyl)pyridine (CAS 1188265-25-9)
- Ethyl 4-(2-((3,5-bis(trifluoromethyl)phenyl)amino)-2-oxoethyl)piperazine-1-carboxylate (CAS 1023882-70-3)
- 6-Amino-4-chloro-1H-indazole-3-carboxylic acid (CAS 885519-31-3)
- 2-(Difluoromethyl)-3-nitropyridine-6-carboxaldehyde (CAS 1805320-03-9)
- 2-ethoxy-6-nitrobenzoic acid (CAS 120277-89-6)
- Lifitegrast Impurity 108 (CAS CATO-C4X-2409108)
- 2-(2,4-Dioxo-1,2-dihydrobenzofuro[3,2-d]pyrimidin-3(4H)-yl)acetic acid (CAS 1707375-57-2)
- D-Phenylalanine, N-[N-[(1,1-dimethylethoxy)carbonyl]-D-leucyl]-, phenylmethyl ester (CAS 159549-97-0)
- 3-Chloro-N-isopropyl-4-methylaniline (CAS 1019585-33-1)
- C-Peptide (human) (CAS 33017-11-7)
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