1-Butyl-N-(4-chlorophenyl)-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamide CAS 300716-25-0
| CAS No. | 300716-25-0 |
| Molecular Formula | C20H19ClN2O3 |
| Molecular Weight | 370.83 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-Butyl-N-(4-chlorophenyl)-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamide (CAS 300716-25-0) is a high-purity analytical reference standard with the molecular formula C20H19ClN2O3 and a molecular weight of 370.83 g/mol.
1-Butyl-N-(4-chlorophenyl)-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamide (C20H19ClN2O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H19ClN2O3 |
| Molecular Weight | 370.83 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- 1-(Morpholinomethyl)-1H-indole-2,3-dione 3-[N-(2-chlorophenyl)hydrazone] (CAS 338391-75-6)
- 2-(Benzofuran-2-yl)-2-(4-(4-chlorophenyl)piperazin-1-yl)acetic acid (CAS 885277-00-9)
- 1-(4-(4-Chlorophenyl)thiazol-2-yl)-4-(4-fluorophenyl)-1H-pyrazol-5-amine (CAS 955965-55-6)
- 3-((4-Chlorophenyl)diazenyl)-1-(morpholinomethyl)-1H-indol-2-ol (CAS 338391-71-2)
- 3-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)phenol (CAS 2557357-27-2)
- 5-Mercapto-[1,2,4]triazolo[4,3-a]pyrimidine-7-sulfonic acid (CAS 189503-76-2)
- (3-Amino-5-fluorophenyl)boronic acid (CAS 1150114-48-9)
- Methyl 3-(2,4-dichlorophenyl)-2-hydroxypropanoate (CAS 875018-66-9)
- (S)-Azepan-2-ylmethanol (CAS 1314999-26-2)
- 1-(4-Fluoro-2-methoxypyridin-3-yl)ethan-1-one (CAS 1823364-48-2)
- methyl 6-nitro-1H-indole-2-carboxylate (CAS 136818-66-1)
- Fosaprepitant Impurity 46 (CAS CATO-C4X-116846)
- (2-(Benzyloxy)-5-formylphenyl)boronic acid (CAS 1310384-22-5)
- Semaglutide impurity 95 (CAS CATO-C4X-222695)
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