6,8-Dichloro-2-(2-chlorophenyl)-4H-benzo[d][1,3]oxazin-4-one CAS 301194-54-7
| CAS No. | 301194-54-7 |
| Molecular Formula | C14H6Cl3NO2 |
| Molecular Weight | 326.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 6,8-Dichloro-2-(2-chlorophenyl)-4H-benzo[d][1,3]oxazin-4-one (C14H6Cl3NO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies 6,8-Dichloro-2-(2-chlorophenyl)-4H-benzo[d][1,3]oxazin-4-one (CAS 301194-54-7), a certified reference material (molecular formula C14H6Cl3NO2, MW 326.56 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H6Cl3NO2 |
| Molecular Weight | 326.56 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Dichloro Standards
- 6,8-Dichloro-2-(4-chlorophenyl)-4H-benzo[d][1,3]oxazin-4-one (CAS 329929-11-5)
- 5,6-Dichloro-2-(2-chloropyridin-3-yl)-1-ethyl-1H-1,3-benzodiazole (CAS 338774-24-6)
- 1,4-Dichloro-2-iodo-3,5,6-trifluorobenzene (CAS 1803766-75-7)
- 1,2-Dichloro-3-iodo-4,5,6-trifluorobenzene (CAS 1803823-57-5)
- 1,3-Dichloro-4-iodo-2,5,6-trifluorobenzene (CAS 1803823-68-8)
- 1,3-Dichloro-2-iodo-4,5,6-trifluorobenzene (CAS 1805483-62-8)
- 1,2-Dichloro-4-iodo-3,5,6-trifluorobenzene (CAS 1806270-45-0)
- 2,2-Dichloro-N-(4-(p-tolylthio)phenyl)acetamide (CAS 339096-21-8)
Recommended Standards
- 2-methylÂeicosanoic acid (CAS 22890-19-3)
- 2,2-Dimethyloctadecanehydrazide (CAS 6079-89-6)
- 7-Chloro-2-(3,4-dichlorophenyl)-4H-benzo[d][1,3]oxazin-4-one (CAS 332033-38-2)
- 1-Amino-2,3,4-trichloroanthracene-9,10-dione (CAS 5355-87-3)
- 1-(2,2-Difluoroethyl)-1h-pyrazole-3-carbaldehyde (CAS 1310379-50-0)
- 4-((3-(Methylcarbamoyl)phenyl)amino)-4-oxobutanoic acid (CAS 941459-49-0)
- 2-(5-phenyl-1H-imidazol-1-yl)acetic acid (CAS 910322-23-5)
- 4-Bromo-6,8-difluoroquinoline (CAS 577692-34-3)
- 3-Nitro-1-{[4-(trifluoromethoxy)phenyl]methyl}-1h-pyrazole (CAS 1240567-71-8)
- 4-Bromo-5-chloro-2-methylbenzene-1-sulfonyl chloride (CAS 1208076-84-9)
- 2-(3-Methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl)-N-(2-phenoxyphenyl)thiazole-4-carboxamide (CAS 956754-14-6)
- 1-(6-(4-Methylpiperazin-1-yl)indolin-1-yl)ethanone (CAS 215162-97-3)
- 7-Bromo-4,5-dihydro-1h-benzo[c]azepin-3(2H)-one (CAS 740842-85-7)
- Semaglutide impurity 196 (CAS CATO-C4X-2226196)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com