3-(Piperidin-4-yl)imidazo[1,5-a]pyridine CAS 301221-44-3
| CAS No. | 301221-44-3 |
| Molecular Formula | C12H15N3 |
| Molecular Weight | 201.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-(Piperidin-4-yl)imidazo[1,5-a]pyridine (CAS 301221-44-3), molecular formula C12H15N3 and molecular weight 201.27 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-(Piperidin-4-yl)imidazo[1,5-a]pyridine (C12H15N3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H15N3 |
| Molecular Weight | 201.27 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
Related Piperidin Standards
- 2-(Piperidin-1-yl)-2-(pyridin-4-yl)acetonitrile (CAS 104742-21-4)
- 2-(Piperidin-1-yl)-2-(pyridin-3-yl)acetonitrile (CAS 104742-85-0)
- 1-(piperidin-3-yl)-1H-1,3-benzodiazole (CAS 1187228-22-3)
- 2-Piperidin-3-yl-1H-benzimidazole (CAS 123771-23-3)
- 3-(Piperidin-4-yl)-1H-indazole (CAS 133455-10-4)
- 2-Methyl-6-(piperidin-1-yl)nicotinonitrile (CAS 1355174-53-6)
- 4-Methyl-6-(piperidin-1-yl)nicotinonitrile (CAS 1355174-65-0)
- 5-Methyl-6-(piperidin-1-yl)nicotinonitrile (CAS 1355222-37-5)
Recommended Standards
- 3-(Piperazin-2-yl)-1H-indole (CAS 886771-50-2)
- 3,5-dimethyl-1-(4-methylphenyl)-1H-pyrazol-4-amine (CAS 63203-92-9)
- 3-(4-Propylphenyl)-1H-pyrazol-5-amine (CAS 501902-77-8)
- 3-[(Piperazin-1-yl)methyl]benzonitrile (CAS 203047-38-5)
- N-(4-Butylphenyl)quinoxaline-6-carboxamide (CAS 881438-07-9)
- 7-Bromo-1-methyl-1,2,3,4-tetrahydroquinoxaline-6-carbonitrile (CAS 1904651-24-6)
- Tauroursodeoxycholic-D4 Acid sodium (CAS 2410279-95-5)
- 2-Ethoxy-2-methylbiphenyl-4-carboxylic acid (CAS 1243559-22-9)
- Janagliflozin impurity 4 (CAS 1800115-25-6)
- 2-Butyl-4-ethoxy-5-hydroxypyridazin-3(2H)-one (CAS 496844-54-3)
- Troxerutin Impurity 15 (CAS 23077-88-5)
- (4R,4'R)-2,2'-(1,3-Diphenylpropane-2,2-diyl)bis(4-benzyl-4,5-dihydrooxazole) (CAS 2279976-00-8)
- N-(1-(3-methyl-1,2,4-oxadiazol-5-yl)cyclohexyl)thiophene-3-carboxamide (CAS 1396800-37-5)
- Tirzepatide Impurity 48 (CAS CATO-C4X-324048)
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