N-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2,4,6-trimethylbenzamide CAS 301306-96-7

Purity 97%+In StockPharmaceutical Standards
CAS No.301306-96-7
Molecular FormulaC18H19NO3
Molecular Weight297.35 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2,4,6-trimethylbenzamide CAS 301306-96-7 chemical structure

Description

The occurrence of N-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2,4,6-trimethylbenzamide is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

N-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2,4,6-trimethylbenzamide (CAS 301306-96-7) is a high-purity analytical reference standard with the molecular formula C18H19NO3 and a molecular weight of 297.35 g/mol.

N-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2,4,6-trimethylbenzamide (C18H19NO3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), N-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2,4,6-trimethylbenzamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC18H19NO3
Molecular Weight297.35 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Nitrogen Atoms1

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