3-Nitro-4-(trifluoromethyl)benzene-1-sulfonyl chloride CAS 301856-45-1

Purity 97%+In StockPharmaceutical Standards
CAS No.301856-45-1
Molecular FormulaC7H3ClF3NO4S
Molecular Weight289.62 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-Nitro-4-(trifluoromethyl)benzene-1-sulfonyl chloride CAS 301856-45-1 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 289.62 g/mol gives 3-Nitro-4-(trifluoromethyl)benzene-1-sulfonyl chloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 3-Nitro-4-(trifluoromethyl)benzene-1-sulfonyl chloride (CAS 301856-45-1), a certified reference material (molecular formula C7H3ClF3NO4S, MW 289.62 g/mol) for analytical method development and quality control.

The molecular framework of 3-Nitro-4-(trifluoromethyl)benzene-1-sulfonyl chloride (C7H3ClF3NO4S) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 3-Nitro-4-(trifluoromethyl)benzene-1-sulfonyl chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC7H3ClF3NO4S
Molecular Weight289.62 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO, water
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF/Cl-containing
Nitrogen Atoms1
Sulfur Atoms1

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