2,2,2-trifluoro-N-[2-(2-hydroxyethoxy)ethyl]acetamide CAS 302331-18-6
| CAS No. | 302331-18-6 |
| Molecular Formula | C6H10F3NO3 |
| Molecular Weight | 201.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2,2,2-trifluoro-N-[2-(2-hydroxyethoxy)ethyl]acetamide (C6H10F3NO3) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 2,2,2-trifluoro-N-[2-(2-hydroxyethoxy)ethyl]acetamide (CAS 302331-18-6), a certified reference material (molecular formula C6H10F3NO3, MW 201.14 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H10F3NO3 |
| Molecular Weight | 201.14 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
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- 3-(2,2,2-Trifluoro-1-hydroxyethyl)benzonitrile (CAS 1226507-37-4)
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Recommended Standards
- 2-(3-Methoxy-4-nitro-1h-pyrazol-1-yl)acetic acid (CAS 512809-53-9)
- 3-Ethoxy-4-nitro-1H-pyrazole-5-carboxylic acid (CAS 400878-02-6)
- 2-Ethoxy-4-nitro-1H-imidazole-5-carboxylic acid (CAS 195817-91-5)
- 6-Hydrazinyl-3-methyl-5-nitropyrimidine-2,4(3H,5H)-dione (CAS 880-83-1)
- 4-(3-Bromophenyl)tetrahydro-2H-pyran-4-ol (CAS 135048-94-1)
- Bis(2-Chlorophenyl)sulfane (CAS 5097-95-0)
- 2-Methyl-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-8-carboxylic acid (CAS 1195159-84-2)
- 3-Chloro-1-isopropylpyrido[2,3-b]pyrazin-2(1H)-one (CAS 1443292-46-3)
- 5-(3-Methoxyphenyl)-1,2-dihydropyrazin-2-one (CAS 88066-90-4)
- 2-Amino-N-cyclopropylbenzamide (CAS 30510-67-9)
- Norepinephrine impurity 134 (CAS CATO-C4X-1514134)
- 5-Bromo-2-(trifluoromethyl)benzonitrile (CAS 1208076-28-1)
- 1-(2-Chlorophenyl)-3-(4-(methylthio)phenyl)propan-1-one (CAS 898781-48-1)
- Semaglutide impurity 290 (CAS CATO-C4X-2226290)
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