Ubidecarenone EP Impurity B CAS 303-95-7
| CAS No. | 303-95-7 |
| Molecular Formula | C44H66O4 |
| Molecular Weight | 658.99 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Ubidecarenone EP Impurity B (CAS 303-95-7, C44H66O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Ubidecarenone EP Impurity B (C44H66O4) contains a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), Ubidecarenone EP Impurity B meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C44H66O4 |
| Molecular Weight | 658.99 g/mol |
| Purity | ≥95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Ubidecarenone Standards
- Ubidecarenone Impurity 1(Coenzyme Q9) (CAS 303-97-9)
- Ubidecarenone impurity 19 (CAS 5677-54-3)
- Ubidecarenone (Coenzyme Q10) Impurity 14 (CAS CATO-C4X-137614)
- Ubidecarenone impurity 21 (CAS CATO-C4X-137621)
- Ubidecarenone impurity 22 (CAS CATO-C4X-137622)
- Ubidecarenone EP Impurity E (CAS 2382-48-1)
- Ubidecarenone Impurity 14 (Coenzyme Q4) (CAS 4370-62-1)
- Ubidecarenone (CAS 303-98-0)
Recommended Standards
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- Arotinolol Impurity 71 (CAS CATO-C4X-185471)
- 1-(4-Nitrophenyl)-1H-pyrazol-4-amine (CAS 62537-82-0)
- Guaifenesin Impurity 7 (CAS 120-80-9)
- Pyruvic acid-DNPH (CAS 790-12-5)
- 1-(4-Bromophenyl)-1,3-diazinane-2,4,6-trione (CAS 251468-84-5)
- (1R,2R)-2-((R)-1-phenylethylamino)cyclohexanol (CAS 98462-58-9)
- 6-Hydroxy-2-methoxypyridine-3-carbonitrile (CAS 130747-60-3)
- D-Ala35-Tirzepatide (CAS CATO-CPTD788904)
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