2-(4-(3-Chlorophenyl)piperazin-1-yl)-N-(5-fluoro-2-methylphenyl)acetamide CAS 303091-59-0
| CAS No. | 303091-59-0 |
| Molecular Formula | C19H21ClFN3O |
| Molecular Weight | 361.84 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 2-(4-(3-Chlorophenyl)piperazin-1-yl)-N-(5-fluoro-2-methylphenyl)acetamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 361.84 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
2-(4-(3-Chlorophenyl)piperazin-1-yl)-N-(5-fluoro-2-methylphenyl)acetamide (CAS 303091-59-0) is a high-purity analytical reference standard with the molecular formula C19H21ClFN3O and a molecular weight of 361.84 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(4-(3-Chlorophenyl)piperazin-1-yl)-N-(5-fluoro-2-methylphenyl)acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H21ClFN3O |
| Molecular Weight | 361.84 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chlorophenyl Standards
- (E)-[1-(4-Chlorophenyl)-2-[4-(2-fluorophenyl)piperazin-1-yl]ethylidene](methoxy)amine (CAS 478049-94-4)
- (E)-{2-[4-(3-chlorophenyl)piperazin-1-yl]-1-(4-fluorophenyl)ethylidene}(methoxy)amine (CAS 672951-78-9)
- (4Z)-1-(4-Chlorophenyl)-3-ethoxy-4-({[(thiophen-2-yl)methyl]amino}methylidene)-4,5-dihydro-1H-pyrazol-5-one (CAS 338751-21-6)
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- 4-(4-((4-Chlorophenyl)sulfonyl)piperazin-1-yl)benzonitrile (CAS 478046-72-9)
- 4-(4-Chlorophenyl)-5-((4-ethoxyphenoxy)methyl)-4h-1,2,4-triazole-3-thiol (CAS 721916-32-1)
- 4-(4-Chlorophenyl)-5-(3,4-dimethoxybenzyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione (CAS 883019-23-6)
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Recommended Standards
- 1-Amino-2-(butylthio)-6-chloro-4-hydroxyanthracene-9,10-dione (CAS 88605-80-5)
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- 2-Tert-butyl 4-ethyl 5-(2-chloroacetamido)-3-methylthiophene-2,4-dicarboxylate (CAS 519016-62-7)
- 4-Chloro-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-N-(p-tolyl)benzamide (CAS 301676-12-0)
- 7-Hydroxy-2,3-dihydrobenzo[b][1,4]dioxine-2-carboxylic acid (CAS 160657-99-8)
- (2-Chlorophenyl)(4-methoxy-3,5-dimethylphenyl)methanone (CAS 951884-41-6)
- N-(9H-Fluoren-2-yl)benzamide (CAS 3671-78-1)
- (4-(Difluoromethyl)-2-iodo-6-methoxypyridin-3-yl)methanol (CAS 1806883-43-1)
- Methyl 3-cyano-5-methyl-1H-pyrrole-2-carboxylate (CAS 203207-05-0)
- 2-(3-Methylpiperidin-1-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 1350748-07-0)
- 2-Cyano-N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)acetamide (CAS 70373-49-8)
- 6-Amino-5-fluoronicotinic acid (CAS 1523095-31-9)
- 4-Bromo-5-(trifluoromethyl)nicotinic acid (CAS 1256813-75-8)
- Experimental Allergic Encephalitogenic Peptide (CAS 29705-92-8)
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