7-(4-Bromophenyl)-2-chloro-6-(4-methoxyphenyl)-7,12-dihydro-6H-chromeno[4,3-d][1,2,4]triazolo[1,5-a]pyrimidine CAS 303094-16-8
| CAS No. | 303094-16-8 |
| Molecular Formula | C25H18BrClN4O2 |
| Molecular Weight | 521.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 7-(4-Bromophenyl)-2-chloro-6-(4-methoxyphenyl)-7,12-dihydro-6H-chromeno[4,3-d][1,2,4]triazolo[1,5-a]pyrimidine is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
7-(4-Bromophenyl)-2-chloro-6-(4-methoxyphenyl)-7,12-dihydro-6H-chromeno[4,3-d][1,2,4]triazolo[1,5-a]pyrimidine (CAS 303094-16-8), molecular formula C25H18BrClN4O2 and molecular weight 521.79 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution, 7-(4-Bromophenyl)-2-chloro-6-(4-methoxyphenyl)-7,12-dihydro-6H-chromeno[4,3-d][1,2,4]triazolo[1,5-a]pyrimidine is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 521.79 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 7-(4-Bromophenyl)-2-chloro-6-(4-methoxyphenyl)-7,12-dihydro-6H-chromeno[4,3-d][1,2,4]triazolo[1,5-a]pyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C25H18BrClN4O2 |
| Molecular Weight | 521.79 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 4 |
Related Bromophenyl Standards
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Recommended Standards
- 2-Chloro-7-iodo-5-(triphenylmethyl)-5H-pyrrolo[2,3-b]pyrazine (CAS 1509941-37-0)
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- 6-Chloro-3-iodo-1-trityl-1H-pyrazolo[4,3-c]pyridine, 97% (CAS 1431719-88-8)
- 2-(1-(2,5-Dichlorophenyl)-1H-pyrazole-4-carbonyl)phenyl (3-chlorophenyl)methanesulfonate (CAS 956910-62-6)
- (4-Bromophenyl)diphenylphosphine Oxide (CAS 5525-40-6)
- 6-(2-Chloroacetyl)-4-propyl-2H-benzo[b][1,4]oxazin-3(4H)-one (CAS 927965-53-5)
- 3-(2-Chlorophenyl)-2,2-difluoro-3-hydroxypropanoic Acid (Mixture of Diastereomers) (CAS 1250734-08-7)
- H-His-Trp-OH (CAS 23403-90-9)
- N2-(4-Chlorophenyl)-5-(2,4-dichlorobenzoyl)-1,3-thiazole-2,4-diamine (CAS 339020-13-2)
- 1-(4-(Dimethylamino)phenyl)ethane-1,2-diol (CAS 149302-71-6)
- 2-Ethyl-4-(trifluoromethyl)pyrimidine-5-carboxylic acid (CAS 500130-77-8)
- 2-((1-Cyanocyclopentyl)amino)-2-oxoethyl 2,3-dimethylquinoxaline-6-carboxylate (CAS 871322-60-0)
- Cyclopropyl(3-isopropyl-1-methyl-1h-1,2,4-triazol-5-yl)methanamine (CAS 1342223-20-4)
- Allo-Thr7-Tirzepatide (CAS CATO-CPTD788933)
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