N-Nitroso-L-hydroxyproline CAS 30310-80-6
| CAS No. | 30310-80-6 |
| Molecular Formula | C5H8N2O4 |
| Molecular Weight | 160.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
N-Nitroso-L-hydroxyproline (CAS 30310-80-6) is a high-purity analytical reference standard with the molecular formula C5H8N2O4 and a molecular weight of 160.13 g/mol.
The molecular framework of N-Nitroso-L-hydroxyproline (C5H8N2O4) is characterized by a carbohydrate-derived structure, an amide group. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), N-Nitroso-L-hydroxyproline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H8N2O4 |
| Molecular Weight | 160.13 g/mol |
| Appearance | White to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1965 |
| Nitrogen Atoms | 2 |
Related N Standards
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- N-Nitroso-Ditertbutylamine (CAS 63819-70-5)
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Recommended Standards
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- 3,6-Dihydro-3-methyl-N-nitro-2H-1,3,5-oxadiazin-4-amine (CAS 153719-38-1)
- Ribavirin Impurity 39 (CAS CATO-C4X-141339)
- 1-(1,1-Difluoroethyl)-2-fluorobenzene (CAS 1138445-14-3)
- 2,5-Bis(2-methoxyethoxy)terephthalic acid (CAS 1265529-85-8)
- Methyl 3-nitro-4-{4-[(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)carbamoyl]piperazin-1-yl}benzoate (CAS 866137-44-2)
- (5-(2-Methoxyphenyl)-1,3,4-oxadiazol-2-yl)methanamine (CAS 944897-80-7)
- 4-Bromo-2-iodo-3-methylpyridine (CAS 1227593-46-5)
- {[3-(Benzyloxy)phenyl]methyl}(butyl)amine (CAS 893611-90-0)
- 1-(3,5-Dichloro-2-fluoropyridin-4-yl)ethan-1-ol (CAS 2887531-07-7)
- 2',5'-Bis((4-aminophenyl)ethynyl)-[1,1':4',1''-terphenyl]-4,4''-dicarbaldehyde (CAS 2375652-87-0)
- N-(2-Fluorophenyl)-2-(4-(thiophen-2-yl)piperidin-1-yl)acetamide (CAS 1396858-35-7)
- 3-(Dimethylamino)-5-(methylthio)phenol (CAS 1243476-67-6)
- Semaglutide impurity 30 (CAS CATO-C4X-222630)
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