N-Isobutyl-6-methylquinazolin-4-amine CAS 303120-23-2
| CAS No. | 303120-23-2 |
| Molecular Formula | C13H17N3 |
| Molecular Weight | 215.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of N-Isobutyl-6-methylquinazolin-4-amine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
N-Isobutyl-6-methylquinazolin-4-amine (CAS 303120-23-2), molecular formula C13H17N3 and molecular weight 215.29 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of N-Isobutyl-6-methylquinazolin-4-amine (C13H17N3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-Isobutyl-6-methylquinazolin-4-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H17N3 |
| Molecular Weight | 215.29 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
Related N Standards
- 1-Isobutyl-3-phenyl-1H-pyrazol-5-amine (CAS 1154324-85-2)
- n-Isobutyl-3-methylquinoxalin-2-amine (CAS 1209850-33-8)
- 1-Isobutyl-2-methyl-1H-indole-3-carbaldehyde (CAS 714278-20-3)
- 3-Isobutyl-1-phenyl-1H-pyrazol-5-amine (CAS 65961-64-0)
- n-Isobutyl-2-((tetrahydro-2h-pyran-4-yl)amino)acetamide (CAS 1153231-24-3)
- Methyl 3-isobutyl-2-isopropyl-3-methyloxirane-2-carboxylate (CAS 1525484-81-4)
- N-isobutyl-1H-indole-5-carboxamide (CAS 104447-76-9)
- 3-Isobutyl-6-methylquinazolin-4(3H)-one (CAS 113260-91-6)
Recommended Standards
- N-ethyl-1-(furan-2-yl)-2-phenylethan-1-amine (CAS 73839-70-0)
- rel-(2R,3R)-tert-Butyl 2-(hydroxymethyl)-3-methylpyrrolidine-1-carboxylate (CAS 2088521-68-8)
- N-ethyl-1-(1H-imidazol-2-yl)-2-phenylethan-1-amine (CAS 886505-02-8)
- rel-(2R,5S)-tert-Butyl 5-hydroxy-2-methylpiperidine-1-carboxylate (CAS 2490154-98-6)
- Benzyl 2-(((2-aminoethyl)(methyl)amino)methyl)piperidine-1-carboxylate (CAS 1353986-78-3)
- N,N’-Diacetyl-L-cystine bis(tert-butyl) diester (CAS 1079950-07-4)
- 6-(Benzyloxy)hexyl methanesulfonate (CAS 170656-31-2)
- 6-Methoxyindolin-7-ol (CAS 70837-64-8)
- Naphtho[2,3-d][1,3]oxazol-2-amine (CAS 1820618-76-5)
- N-Chloromethanamine (CAS 6154-14-9)
- 1-(4-Bromophenyl)hexan-1-ol (CAS 71434-62-3)
- Boronic acid, b-[3-[[[(2-fluorophenyl)methyl]amino]carbonyl]phenyl]- (CAS 874288-21-8)
- 2-(Tetrahydro-2H-pyran-2-yl)pyrrolidine hydrochloride (CAS 2137740-10-2)
- Insulin degludec (CAS 844439-96-9)
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