1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-1,2,4-triazol-3-amine CAS 303144-49-2
| CAS No. | 303144-49-2 |
| Molecular Formula | C8H5ClF3N5 |
| Molecular Weight | 263.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-1,2,4-triazol-3-amine (CAS 303144-49-2), molecular formula C8H5ClF3N5 and molecular weight 263.61 g/mol, is a CATO reference standard with documented purity and traceability.
1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-1,2,4-triazol-3-amine (C8H5ClF3N5) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-1,2,4-triazol-3-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H5ClF3N5 |
| Molecular Weight | 263.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 5 |
Related Chloro Standards
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Recommended Standards
- Zinc(II) Acetylacetonate (CAS 14024-63-6)
- Gadolinium(III) chloride solution (CAS 10138-52-0)
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- N-(8-Chloroimidazo[1,2-a]pyridin-2-yl)-2,2,2-trifluoroacetamide (CAS 2006277-79-6)
- (2,6-Dimethylpyridine-3,5-diyl)dimethanol (CAS 70993-72-5)
- (R)-1-(3-Fluoro-5-methoxyphenyl)ethan-1-amine (CAS 1213489-31-6)
- 3-Bromo-5-chloro-4-fluorophenacyl bromide (CAS 1805576-82-2)
- MDL 72274A (CAS 85278-24-6)
- Ethyl 4,6-dihydroxy-2-oxo-2H-chromene-3-carboxylate (CAS 100037-65-8)
- 3-(Bromomethyl)-4-(difluoromethyl)pyridin-2-amine (CAS 1805257-70-8)
- 2-(4-Butoxyphenyl)furan (CAS 69836-65-3)
- Famciclovir Impurity 23 (CAS CATO-C4X-164223)
- 2-(4-Cyclohexylphenoxy)-5-(trifluoromethyl)aniline (CAS 329063-84-5)
- ((Cys31,Nva34)-Neuropeptide Y (27-36))2 (CAS 172997-92-1)
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