3-((2-Chloro-6-fluorobenzyl)oxy)-2-methyl-3'-nitro-4H-[1,2'-bipyridin]-4-one CAS 303144-66-3
| CAS No. | 303144-66-3 |
| Molecular Formula | C18H13ClFN3O4 |
| Molecular Weight | 389.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 389.76 g/mol gives 3-((2-Chloro-6-fluorobenzyl)oxy)-2-methyl-3'-nitro-4H-[1,2'-bipyridin]-4-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3-((2-Chloro-6-fluorobenzyl)oxy)-2-methyl-3'-nitro-4H-[1,2'-bipyridin]-4-one (CAS 303144-66-3) is a high-purity analytical reference standard with the molecular formula C18H13ClFN3O4 and a molecular weight of 389.76 g/mol.
The molecular framework of 3-((2-Chloro-6-fluorobenzyl)oxy)-2-methyl-3'-nitro-4H-[1,2'-bipyridin]-4-one (C18H13ClFN3O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-((2-Chloro-6-fluorobenzyl)oxy)-2-methyl-3'-nitro-4H-[1,2'-bipyridin]-4-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H13ClFN3O4 |
| Molecular Weight | 389.76 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
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Recommended Standards
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- 7-Bromo-2-chloro-3-((2-(trimethylsilyl)ethoxy)methyl)quinazolin-4(3H)-one (CAS 2659373-00-7)
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- Ethyl 4,7-dibromoquinoline-3-carboxylate (CAS 2180727-08-4)
- Samarium(III) thenoyltrifluoroacetonate (CAS 41884-73-5)
- 2-(2,6-Difluoro-4-(trifluoromethyl)phenoxy)-4-fluoroaniline (CAS 2244088-77-3)
- 3-Octylthiophene (CAS 65016-62-8)
- Methyl 2,3,4-trifluorobenzoate (CAS 773873-68-0)
- Tri-m-tolylphosphine (CAS 6224-63-1)
- 4,7-Dibromo-[1,2,5]thiadiazolo[3,4-c]pyridine (CAS 333432-27-2)
- 5-Hexylpyrimidine-2,4,6-triamine (CAS 94087-72-6)
- tert-Butyl 3-[(3-tert-butyl-1,2,4-oxadiazol-5-yl)methyl]azetidine-1-carboxylate (CAS 1692345-31-5)
- Gastric Inhibitory Polypeptide (1-30) amide (porcine) (CAS 134846-93-8)
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