1-Benzyl-3-((2-chloro-6-fluorobenzyl)oxy)-2-methylpyridin-4(1H)-one CAS 303144-74-3
| CAS No. | 303144-74-3 |
| Molecular Formula | C20H17ClFNO2 |
| Molecular Weight | 357.81 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 1-Benzyl-3-((2-chloro-6-fluorobenzyl)oxy)-2-methylpyridin-4(1H)-one (CAS 303144-74-3), a certified reference material (molecular formula C20H17ClFNO2, MW 357.81 g/mol) for analytical method development and quality control.
The molecular framework of 1-Benzyl-3-((2-chloro-6-fluorobenzyl)oxy)-2-methylpyridin-4(1H)-one (C20H17ClFNO2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-Benzyl-3-((2-chloro-6-fluorobenzyl)oxy)-2-methylpyridin-4(1H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H17ClFNO2 |
| Molecular Weight | 357.81 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- Methyl 5-methyl-2-(2H-1,2,3-triazol-2-yl)benzoate (CAS 1787266-70-9)
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- 1-(4-Hydroxyphenyl)-1,3,3-trimethyl-2,3-dihydro-1H-inden-5-ol (CAS 109252-41-7)
- Peptide YY (3-36) (human) (CAS 123583-37-9)
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