N,N-dimethyl-6-((phenylthio)methyl)-2-(pyridin-3-yl)pyrimidin-4-amine CAS 303147-59-3

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

N,N-dimethyl-6-((phenylthio)methyl)-2-(pyridin-3-yl)pyrimidin-4-amine (CAS 303147-59-3), molecular formula C18H18N4S and molecular weight 322.43 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of N,N-dimethyl-6-((phenylthio)methyl)-2-(pyridin-3-yl)pyrimidin-4-amine (C18H18N4S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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