2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-N'-[2-(4-chlorophenoxy)ethanimidoyl]acetohydrazide CAS 303147-87-7
| CAS No. | 303147-87-7 |
| Molecular Formula | C16H14Cl2F3N5O2 |
| Molecular Weight | 436.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-N'-[2-(4-chlorophenoxy)ethanimidoyl]acetohydrazide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-N'-[2-(4-chlorophenoxy)ethanimidoyl]acetohydrazide (CAS 303147-87-7), a certified reference material (molecular formula C16H14Cl2F3N5O2, MW 436.22 g/mol) for analytical method development and quality control.
2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-N'-[2-(4-chlorophenoxy)ethanimidoyl]acetohydrazide (C16H14Cl2F3N5O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H14Cl2F3N5O2 |
| Molecular Weight | 436.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 5 |
Related chloro Standards
- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(4-chlorophenyl)-1H-pyrrole-2-sulfonamide (CAS 338397-95-8)
- 5-[Benzyl-(4-chloro-phenyl)-sulfamoyl]-2-chloro-benzoic acid (CAS 735322-07-3)
- 3-{[(2-chloro-6-fluorophenyl)methyl]sulfanyl}-5-[(E)-2-[(4-chlorophenyl)amino]ethenyl]-1,2-thiazole-4-carbonitrile (CAS 338778-77-1)
- 1-((2-Chloro-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methyl)-N-cyclobutyl-N-methylpiperidin-4-amine (CAS 1147423-09-3)
- N-(2-Chloro-4,6-dimethylphenyl)-2-((3-ethyl-5,6-dimethyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)thio)acetamide (CAS 579446-87-0)
- 5-Chloro-2-(2-naphthyl)benzimidazole (CAS 7235-72-5)
- 2-Chloro-N-((2-(2,3-dimethylphenyl)benzo[d]oxazol-5-yl)carbamothioyl)benzamide (CAS 590396-77-3)
- 3-Chloro-N-((2-(2,3-dimethylphenyl)benzo[d]oxazol-5-yl)carbamothioyl)benzamide (CAS 590396-64-8)
Recommended Standards
- 2,7-Dibromo-3,6-di-tert-butyl-9H-fluorene (CAS 106112-41-8)
- 6,8-Dibromo-2-(((tert-butyldimethylsilyl)oxy)methyl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrazine (CAS 2428557-55-3)
- Fluralaner impurity 36 (CAS CATO-C4X-218036)
- 6,8-Dibromo-2-(2-((tert-butyldimethylsilyl)oxy)ethyl)-[1,2,4]triazolo[1,5-a]pyrazine (CAS 2428557-57-5)
- 4-(Hydroxymethyl)-1-methyl-1H-pyrazole-5-sulfonamide (CAS 117519-42-3)
- (2-(2,5-Dichlorophenyl)cyclopropyl)methanamine (CAS 1315344-80-9)
- 4-Bromo-1-(difluoromethyl)-1H-imidazole (CAS 1216310-31-4)
- 1-(2-(3-Methylpyridin-2-yl)thiazol-5-yl)ethan-1-one (CAS 1248387-59-8)
- Ethyl 4-phenyl-2-(pyridin-4-yl)pyrimidine-5-carboxylate (CAS 503175-53-9)
- 2,5-Di-tert-butyl-1H-indole-3-carbaldehyde (CAS 590347-37-8)
- tert-butyl 4-isopropyl-2,2-dioxo-oxathiazolidine-3-carboxylate (CAS 1824511-18-3)
- Lumateperone Impurity 74 Tosylate (CAS CATO-C4X-220174)
- 2-(1-Naphthylamino)propanohydrazide (CAS 1396972-42-1)
- Pancreatic Polypeptide (31-36) Free Acid, human (CAS 192432-73-8)
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