4-(2,6-Dichlorophenyl)-2-[(E)-2-(dimethylamino)ethenyl]-6-methylpyridine-3,5-dicarbonitrile CAS 303148-14-3
| CAS No. | 303148-14-3 |
| Molecular Formula | C18H14Cl2N4 |
| Molecular Weight | 357.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
4-(2,6-Dichlorophenyl)-2-[(E)-2-(dimethylamino)ethenyl]-6-methylpyridine-3,5-dicarbonitrile (CAS 303148-14-3), molecular formula C18H14Cl2N4 and molecular weight 357.24 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, 4-(2,6-Dichlorophenyl)-2-[(E)-2-(dimethylamino)ethenyl]-6-methylpyridine-3,5-dicarbonitrile is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 357.24 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), 4-(2,6-Dichlorophenyl)-2-[(E)-2-(dimethylamino)ethenyl]-6-methylpyridine-3,5-dicarbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H14Cl2N4 |
| Molecular Weight | 357.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
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Recommended Standards
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- 1-Bromo-6-phenylpyrene (CAS 294881-47-3)
- 4-Hydroxy-3-methylbenzenesulfonic Acid (CAS 7134-04-5)
- 7-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione 7-Deaza-2'-deoxyxanthosine 96022-82-1 (CAS 96022-82-1)
- 3-(4-Bromophenyl)-5-chloroisoxazole (CAS 192432-78-3)
- 7-Chloro-5-(6-phenylpyridin-2-yl)thiazolo[4,5-d]pyrimidine (CAS 1332471-80-3)
- 5-Methyl-2-((trimethylsilyl)methyl)pyridine (CAS 158588-03-5)
- 2-(4-Ethylphenyl)butan-2-ol (CAS 312904-57-7)
- (R)-1-(Pyridin-3-ylmethyl)-3-(pyrrolidin-3-yl)urea hydrochloride (CAS 1439894-60-6)
- 2,3-Difluoro-4-methoxybenzyl alcohol (CAS 886500-71-6)
- 3-(Piperidin-3-yloxy)benzonitrile (CAS 902836-93-5)
- Endo-Pro36-Tirzepatide (CAS CATO-CPTD788688)
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