Methyl 2-[1-(3-hydroxyphenyl)ethylidene]-1-hydrazinecarboxylate CAS 303148-72-3

Purity 97%+In StockPharmaceutical Standards
CAS No.303148-72-3
Molecular FormulaC10H12N2O3
Molecular Weight208.21 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Methyl 2-[1-(3-hydroxyphenyl)ethylidene]-1-hydrazinecarboxylate CAS 303148-72-3 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Methyl 2-[1-(3-hydroxyphenyl)ethylidene]-1-hydrazinecarboxylate.

Methyl 2-[1-(3-hydroxyphenyl)ethylidene]-1-hydrazinecarboxylate (CAS 303148-72-3) is a high-purity analytical reference standard with the molecular formula C10H12N2O3 and a molecular weight of 208.21 g/mol.

The molecular framework of Methyl 2-[1-(3-hydroxyphenyl)ethylidene]-1-hydrazinecarboxylate (C10H12N2O3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), Methyl 2-[1-(3-hydroxyphenyl)ethylidene]-1-hydrazinecarboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC10H12N2O3
Molecular Weight208.21 g/mol
AppearanceOff-white to pale yellow crystalline powder. (faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Nitrogen Atoms2

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