(E)-6-(2-chloro-4-fluorostyryl)-4,4-dimethyl-2-(methylthio)-1,4-dihydropyrimidine CAS 303148-79-0
| CAS No. | 303148-79-0 |
| Molecular Formula | C15H16ClFN2S |
| Molecular Weight | 310.82 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 310.82 g/mol gives (E)-6-(2-chloro-4-fluorostyryl)-4,4-dimethyl-2-(methylthio)-1,4-dihydropyrimidine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
(E)-6-(2-chloro-4-fluorostyryl)-4,4-dimethyl-2-(methylthio)-1,4-dihydropyrimidine (CAS 303148-79-0) is a high-purity analytical reference standard with the molecular formula C15H16ClFN2S and a molecular weight of 310.82 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution, (E)-6-(2-chloro-4-fluorostyryl)-4,4-dimethyl-2-(methylthio)-1,4-dihydropyrimidine is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 310.82 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (E)-6-(2-chloro-4-fluorostyryl)-4,4-dimethyl-2-(methylthio)-1,4-dihydropyrimidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H16ClFN2S |
| Molecular Weight | 310.82 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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- 5-(Benzylthio)-1H-1,2,4-triazole-3(2H)-thione (CAS 112729-17-6)
- 4-Chloro-N-{[4-(prop-2-en-1-yl)-5-({[4-(trifluoromethyl)phenyl]methyl}sulfanyl)-4H-1,2,4-triazol-3-yl]methyl}benzene-1-sulfonamide (CAS 338422-25-6)
- 5-Amino-4-chloro-1H-benzo[d]imidazol-2(3H)-one (CAS 72735-26-3)
- 1-(4-Dimethylamino-phenyl)-5-oxo-pyrrolidine-3-carboxylic acid (CAS 346644-26-6)
- 4-(Isothiazol-5-yl)aniline (CAS 904085-99-0)
- 8-Nitronaphthalene-1,3,5-trisulfonic acid (CAS 66620-35-7)
- Semaglutide impurity 86 (CAS CATO-C4X-152686)
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