(E)-[3-(4-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}phenyl)-3-oxopropylidene](methyl)oxidoazanium CAS 303151-65-7
| CAS No. | 303151-65-7 |
| Molecular Formula | C20H20ClF3N4O2 |
| Molecular Weight | 440.85 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(E)-[3-(4-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}phenyl)-3-oxopropylidene](methyl)oxidoazanium (CAS 303151-65-7), molecular formula C20H20ClF3N4O2 and molecular weight 440.85 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, (E)-[3-(4-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}phenyl)-3-oxopropylidene](methyl)oxidoazanium is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 440.85 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures (E)-[3-(4-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}phenyl)-3-oxopropylidene](methyl)oxidoazanium under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H20ClF3N4O2 |
| Molecular Weight | 440.85 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related E Standards
- 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N'-[(1E)-(4-methoxyphenyl)methylidene]piperidine-4-carbohydrazide (CAS 338761-38-9)
- Ethyl 6-chloro-4-((2-nitrobenzyl)sulfonyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-2-carboxylate (CAS 866134-55-6)
- 3-Chloro-2-oxopropyl 2-(N-((4,6-dimethylpyrimidin-2-yl)carbamoyl)sulfamoyl)benzoate (CAS 1781241-33-5)
- N-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}phenyl)-4-methylbenzene-1-sulfonamide (CAS 478246-36-5)
- 4-[4-[5-(5-Chloro-6-isopropoxy-3-pyridyl)-1,2,4-oxadiazol-3-yl]-1-indolyl]butanoic Acid (CAS 1034688-30-6)
- 4-(4-((3-(5-Chloro-2-methoxyphenyl)ureido)methyl)phenoxy)-N-methylpicolinamide (CAS 1349244-89-8)
- 4-[2-[5-Chloro-1,2-dihydro-2-oxo-1-(phenylmethyl)-3H-indol-3-ylidene]hydrazinyl]benzenesulfonamide (CAS 2380245-48-5)
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Recommended Standards
- Apixaban Impurity 58 (CAS CATO-C4X-108858)
- (4Z)-4-[(4-Chlorophenyl)methylidene]-1-(4-fluorophenyl)-2-[(3,4,4-trifluorobut-3-en-1-yl)sulfanyl]-4,5-dihydro-1H-imidazol-5-one (CAS 477886-74-1)
- Thallium(I) sulfide (CAS 1314-97-2)
- tert-Butyl (1S,4R)-6-((4-chloro-5-(trifluoromethyl)pyrimidin-2-yl)amino)-1,2,3,4-tetrahydro-1,4-epiminonaphthalene-9-carboxylate (CAS 942492-24-2)
- 2-Propenoic acid, 2-methyl-, 2-[(1,1-dimethylethyl)amino]ethyl ester, polymer with methyl 2-methyl-2-propenoate and 2-methylpropyl 2-methyl-2-propenoate (CAS 68516-42-7)
- 2-(Ethylthio)-1-(3-nitrophenyl)ethan-1-one (CAS 1157361-52-8)
- Methyl 2-(2-chloro-6-fluorophenyl)-4-(4-chlorophenyl)-4-oxobutanoate (CAS 344281-42-1)
- 1-(5-Cyclopropyl-1,2,4-oxadiazol-3-yl)ethan-1-amine (CAS 1155955-73-9)
- 2-Hydroxy-4-methylpyridine-d3 (CAS 1185316-03-3)
- 1-(4-Fluorophenylsulfonyl)piperidine (CAS 312-32-3)
- N,N-Bis(4-fluorobenzyl)-1-(piperidin-2-yl)methanamine hydrochloride (CAS 1261235-15-7)
- N-Benzyl-3-(2-sulfanylidene-2,3-dihydro-1H-imidazol-1-yl)benzamide (CAS 1146290-00-7)
- 3,5,6-Trifluoropyridazin-4-amine (CAS 7679-50-7)
- Liraglutide Impurity 15 TFA Salt (CAS CATO-C4X-199215)
Why CATO?
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