N-(2,4-difluorophenyl)-3-(4-fluoro-2-nitrophenoxy)thiophene-2-carboxamide CAS 303152-73-0
| CAS No. | 303152-73-0 |
| Molecular Formula | C17H9F3N2O4S |
| Molecular Weight | 394.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
N-(2,4-difluorophenyl)-3-(4-fluoro-2-nitrophenoxy)thiophene-2-carboxamide (CAS 303152-73-0) is a high-purity analytical reference standard with the molecular formula C17H9F3N2O4S and a molecular weight of 394.32 g/mol.
N-(2,4-difluorophenyl)-3-(4-fluoro-2-nitrophenoxy)thiophene-2-carboxamide (C17H9F3N2O4S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-(2,4-difluorophenyl)-3-(4-fluoro-2-nitrophenoxy)thiophene-2-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H9F3N2O4S |
| Molecular Weight | 394.32 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related N Standards
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Recommended Standards
- 4-Benzyl-5-[3-(2,4-dichlorophenoxy)propyl]-4H-1,2,4-triazole-3-thiol (CAS 885267-51-6)
- tert-Butyl 4-((4-bromobenzyl)amino)-4-cyanopiperidine-1-carboxylate (CAS 2445225-39-6)
- (3R,4R)-Gemcitabine Impurity 23 (CAS CATO-C4X-137223)
- N-{2-[3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl]pyridin-3-yl}hexanamide (CAS 956779-82-1)
- 1-Acetyl-4,4-dimethyl-1,2,3,4-tetrahydroquinoline-6-sulfonyl chloride (CAS 2138227-11-7)
- Ethyl 7-cyano-2-(trifluoromethyl)imidazo[1,2-a]pyridine-3-carboxylate (CAS 1555847-50-1)
- 4-Ethyl-5-fluoro-2-methoxyphenol (CAS 1065076-45-0)
- Ethyl 4-(benzofuran-2-yl)-2-oxopyrrolidine-3-carboxylate (CAS 88234-82-6)
- Metaraminol Impurity 107 Fumarate (CAS CATO-C4X-2252107)
- N-Butyl-8-methyl-8-azabicyclo[3.2.1]octan-3-amine (CAS 1132886-55-5)
- Labetalol Impurity 78 (CAS CATO-C4X-246678)
- [4-(4-Methoxyphenyl)-4H-1,2,4-triazol-3-yl]methanamine dihydrochloride (CAS 1351609-10-3)
- Methyl N-(3-chlorophenyl)-N-((4-chlorophenyl)sulfonyl)glycinate (CAS 527757-89-7)
- Pancreatic Polypeptide (rat) (CAS 90419-12-8)
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