{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}urea CAS 303153-07-3
| CAS No. | 303153-07-3 |
| Molecular Formula | C8H8ClF3N4O |
| Molecular Weight | 268.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of {[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}urea is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}urea (CAS 303153-07-3) is a high-purity analytical reference standard with the molecular formula C8H8ClF3N4O and a molecular weight of 268.62 g/mol.
The molecular framework of {[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}urea (C8H8ClF3N4O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures {[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}urea under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H8ClF3N4O |
| Molecular Weight | 268.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related chloro Standards
- 2-[4-chloro-5-cyclopropyl-3-(trifluoromethyl)-1h-pyrazol-1-yl]acetic acid (CAS 1006447-79-5)
- 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}propanoic acid (CAS 1016839-74-9)
- Methyl (3-chloro-5-(trifluoromethyl)pyridin-2-yl)glycinate (CAS 1041559-46-9)
- 3-(5-Chloro-2-(trifluoromethoxy)phenyl)propanoic acid (CAS 1092461-23-8)
- Methyl (6-chloro-4-(trifluoromethyl)-pyridin-2-ylmethylcarbamate (CAS 1160994-80-8)
- Ethyl 2-chloro-5-(trifluoromethoxy)benzoate (CAS 1261619-29-7)
- 3-(3-Chloro-4-(trifluoromethoxy)phenyl)propanoic acid (CAS 1261873-29-3)
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Recommended Standards
- Methyl 2-[4-chloro-3-(trifluoromethyl)phenoxy]-acetate (CAS 1965304-83-9)
- 2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)amino)acetohydrazide (CAS 446276-13-7)
- (3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-L-alanine (CAS 1938562-70-9)
- 3-(3-Chloro-5-(trifluoromethoxy)phenyl)propanoic acid (CAS 916420-74-1)
- 1-(2-Hydroxy-4-((tetrahydro-2H-pyran-2-yl)oxy)phenyl)-2-(4-((tetrahydro-2H-pyran-2-yl)oxy)phenyl)ethanone (CAS 130064-21-0)
- 4-Iodo-N,N,N-trimethylbutan-1-aminium iodide (CAS 89499-99-0)
- N-(4-tert-Butyl-1,3-thiazol-2-yl)acetamide (CAS 82245-97-4)
- 1-Bromonaphthalene-D7 (CAS 37621-57-1)
- 3-Bromo-N-(2,3-dimethylphenyl)benzamide (CAS 331270-85-0)
- 1-(3-Methylenecyclobutyl)ethanone (CAS 25303-66-6)
- (4-Methoxypyridin-2-yl)methanamine hydrochloride (CAS 1956342-04-3)
- S-tert-Butyl-L-cysteine HCl (CAS 2481-09-6)
- 1-Methyl-N-(pyridin-3-yl)-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide (CAS 477709-07-2)
- Liraglutide(14-22)TFA Salt (CAS CATO-C4X-199212)
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