1-Chloro-3-(4-fluorophenyl)propan-2-one CAS 303967-88-6

Purity 97%+In StockPharmaceutical Standards
CAS No.303967-88-6
Molecular FormulaC9H8ClFO
Molecular Weight186.61 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-Chloro-3-(4-fluorophenyl)propan-2-one CAS 303967-88-6 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-Chloro-3-(4-fluorophenyl)propan-2-one.

1-Chloro-3-(4-fluorophenyl)propan-2-one (CAS 303967-88-6), molecular formula C9H8ClFO and molecular weight 186.61 g/mol, is a CATO reference standard with documented purity and traceability.

Based on its molecular formula C9H8ClFO, 1-Chloro-3-(4-fluorophenyl)propan-2-one contains a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 186.61 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC9H8ClFO
Molecular Weight186.61 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF/Cl-containing

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Why CATO?