2-(Methylthio)-4-(p-tolyl)-6-(m-tolylthio)pyrimidine-5-carbonitrile CAS 303985-03-7

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(Methylthio)-4-(p-tolyl)-6-(m-tolylthio)pyrimidine-5-carbonitrile.

2-(Methylthio)-4-(p-tolyl)-6-(m-tolylthio)pyrimidine-5-carbonitrile (CAS 303985-03-7), molecular formula C20H17N3S2 and molecular weight 363.50 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 2-(Methylthio)-4-(p-tolyl)-6-(m-tolylthio)pyrimidine-5-carbonitrile (C20H17N3S2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Why CATO?

• ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
• 130,000+ catalog items in stock, COA supplied with every batch
• Worldwide shipping with full export documentation (HS code guidance available)
• Technical support: +86 18665070610 / Nicole.chen@cato-chem.com