4-(4-Methylpiperazin-1-yl)-6-phenyl-2-({[3-(trifluoromethyl)phenyl]methyl}sulfanyl)pyrimidine-5-carbonitrile CAS 303985-69-5
| CAS No. | 303985-69-5 |
| Molecular Formula | C24H22F3N5S |
| Molecular Weight | 469.53 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 469.53 g/mol gives 4-(4-Methylpiperazin-1-yl)-6-phenyl-2-({[3-(trifluoromethyl)phenyl]methyl}sulfanyl)pyrimidine-5-carbonitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4-(4-Methylpiperazin-1-yl)-6-phenyl-2-({[3-(trifluoromethyl)phenyl]methyl}sulfanyl)pyrimidine-5-carbonitrile (CAS 303985-69-5), molecular formula C24H22F3N5S and molecular weight 469.53 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 4-(4-Methylpiperazin-1-yl)-6-phenyl-2-({[3-(trifluoromethyl)phenyl]methyl}sulfanyl)pyrimidine-5-carbonitrile (C24H22F3N5S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 15.0, corresponding to approximately 15 ring(s) or double-bond equivalent(s). With a molecular weight of 469.53 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-(4-Methylpiperazin-1-yl)-6-phenyl-2-({[3-(trifluoromethyl)phenyl]methyl}sulfanyl)pyrimidine-5-carbonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H22F3N5S |
| Molecular Weight | 469.53 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Methylpiperazin Standards
- 4-(4-Methylpiperazin-1-yl)-2-[(tetrahydropyran-4-yl)(2,2,2-trifluoroacetyl)amino]benzoic acid tert-butyl ester (CAS 1034975-53-5)
- 3,6-Bis(2-(4-methylpiperazin-1-yl)ethoxy)acridine (CAS 81541-35-7)
- N-(4-(4-Methylpiperazin-1-yl)phenyl)-4-(3-nitrophenoxy)thieno[3,2-d]pyrimidin-2-amine (CAS 1353553-08-8)
- 6-(4-Methylpiperazin-1-yl)-2'-(naphthalen-2-yl)-1H,3'H-2,5'-bibenzo[d]imidazole (CAS 23491-55-6)
- 4-(4-methylpiperazin-1-yl)-1-(phenylsulfonyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine (CAS 1203566-62-4)
- 3-(4-Methylpiperazin-1-yl)-N-(3-nitrobenzyl)-7-(trifluoromethyl)quinolin-5-amine (CAS 1268264-10-3)
- 4-(3-(7-(4-Methylpiperazin-1-yl)-1H-benzo[d]imidazol-2-yl)-1H-indazol-6-yl)aniline (CAS 1132609-87-0)
- 5-(4-(4-Methylpiperazin-1-yl)phenyl)-N-(3-(trifluoromethyl)phenyl)-1H-pyrazole-1-carboxamide (CAS 321998-93-0)
Recommended Standards
- (E)-Ethyl (3-(4-((3-methyl-4-((6-methylpyridin-3-yl)-oxy)phenyl)amino)quinazolin-6-yl)allyl)carbamate (CAS 537705-08-1)
- 4-{2-[2-(4-fluorophenoxy)ethoxy]ethoxy}-1-(4-methylbenzenesulfonyl)-1H-indole (CAS 477856-57-8)
- (1,4,5-Triphenyl-1H-pyrrole-2,3-diyl)bis(methylene) bis(methylcarbamate) (CAS 72572-65-7)
- 5-(3-Ethoxy-4-hydroxyphenyl)-3-hydroxy-4-(4-isopropoxy-3-methylbenzoyl)-1-(2-methoxyethyl)-1H-pyrrol-2(5H)-one (CAS 371144-88-6)
- 5-Chloro-3-(thiophene-2-carboxylhydrazidyl)-2-oxoindoline (CAS 519147-16-1)
- 6-Bromobenzo[d]oxazol-4-ol (CAS 2791314-03-7)
- 1-(3,4-Difluorophenyl)ethane-1-thiol (CAS 1152550-43-0)
- Alectinib Impurity 86 (CAS CATO-C4X-283686)
- Bevantolol Impurity 25 (CAS CATO-C4X-241125)
- 2-{2-Cyclopropyl-7-fluoro-1H-benzo[d]imidazol-1-yl}acetic acid (CAS 1509413-45-9)
- 6-Bromo-1,4-dioxaspiro[4.4]nonane (CAS 82235-82-3)
- (E)-4-(4-Fluorostyryl)-2,6-dimethylphenol (CAS 125722-16-9)
- Ethyl 2-(3-chlorobenzo[b]thiophene-2-carboxamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate (CAS 313960-53-1)
- Semaglutide impurity 39 (CAS CATO-C4X-222639)
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