4-[(1Z)-{[(4-fluorophenyl)methoxy]imino}methyl]-2-[(4-methoxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-1,3-dione CAS 303986-08-5
| CAS No. | 303986-08-5 |
| Molecular Formula | C25H21FN2O4 |
| Molecular Weight | 432.44 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-[(1Z)-{[(4-fluorophenyl)methoxy]imino}methyl]-2-[(4-methoxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-1,3-dione is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-[(1Z)-{[(4-fluorophenyl)methoxy]imino}methyl]-2-[(4-methoxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-1,3-dione (CAS 303986-08-5), molecular formula C25H21FN2O4 and molecular weight 432.44 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 4-[(1Z)-{[(4-fluorophenyl)methoxy]imino}methyl]-2-[(4-methoxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-1,3-dione is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 432.44 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-[(1Z)-{[(4-fluorophenyl)methoxy]imino}methyl]-2-[(4-methoxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-1,3-dione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C25H21FN2O4 |
| Molecular Weight | 432.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Z Standards
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Recommended Standards
- 2-((2,4-Difluoro-N-(4-methoxyphenyl)phenyl)sulfonamido)-N-phenylacetamide (CAS 852917-90-9)
- Methyl 4-((4-(4-fluorobenzoyl)-3-methyl-2-oxo-3,4-dihydroquinoxalin-1(2H)-yl)methyl)benzoate (CAS 317833-42-4)
- 1,3,5-Trifluoro-2,4,6-tris(phenylethynyl)benzene (CAS 674289-04-4)
- MRE-3008F20 (CAS 252979-43-4)
- 2-(4-(4-Acetylphenyl)piperazine-1-carbonyl)-5-(benzyloxy)-4H-pyran-4-one (CAS 1021024-06-5)
- tert-Butyl (5-chloro-2-(methylsulfonyl)pyrimidin-4-yl)carbamate (CAS 955112-59-1)
- 2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-methylthiazole-4-carboxylic acid (CAS 885952-97-6)
- Propyl β-D-Glucuronide (CAS 17685-07-3)
- 5-[(3-Chlorophenyl)sulfanyl]-N-(4-fluorophenyl)-1,3-dimethyl-1H-pyrazole-4-carboxamide (CAS 303998-08-5)
- 3-(o-Tolyloxy)azetidine hydrochloride (CAS 1269054-46-7)
- Repaglinide Methyl Ester (CAS 800365-89-3)
- 4-(4-Chlorophenoxy)-N,N-dimethyl-6-(trifluoromethyl)pyrimidin-2-amine (CAS 338792-32-8)
- 3-(Difluoromethyl)-5-(hydroxymethyl)-4-methoxypicolinonitrile (CAS 1807104-31-9)
- Tirzepatide Impurity 14 (CAS CATO-C4X-324014)
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