4-(Dimethylamino)-2-(1H-1,2,4-triazol-1-yl)nicotinonitrile CAS 303986-31-4

Purity 97%+In StockPharmaceutical Standards
CAS No.303986-31-4
Molecular FormulaC10H10N6
Molecular Weight214.23 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-(Dimethylamino)-2-(1H-1,2,4-triazol-1-yl)nicotinonitrile CAS 303986-31-4 chemical structure

Description

The occurrence of 4-(Dimethylamino)-2-(1H-1,2,4-triazol-1-yl)nicotinonitrile is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

4-(Dimethylamino)-2-(1H-1,2,4-triazol-1-yl)nicotinonitrile (CAS 303986-31-4) is a high-purity analytical reference standard with the molecular formula C10H10N6 and a molecular weight of 214.23 g/mol.

The molecular framework of 4-(Dimethylamino)-2-(1H-1,2,4-triazol-1-yl)nicotinonitrile (C10H10N6) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 4-(Dimethylamino)-2-(1H-1,2,4-triazol-1-yl)nicotinonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC10H10N6
Molecular Weight214.23 g/mol
AppearancePale yellow to yellow crystalline powder. (faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Nitrogen Atoms6

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