4-Hydroxy-N-(4-iodophenyl)-2-oxo-1-azatricyclo[7.3.1.0^{5,13}]trideca-3,5(13),6,8-tetraene-3-carboxamide CAS 303987-36-2
| CAS No. | 303987-36-2 |
| Molecular Formula | C19H15IN2O3 |
| Molecular Weight | 446.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Hydroxy-N-(4-iodophenyl)-2-oxo-1-azatricyclo[7.3.1.0^{5,13}]trideca-3,5(13),6,8-tetraene-3-carboxamide (C19H15IN2O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, iodine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
4-Hydroxy-N-(4-iodophenyl)-2-oxo-1-azatricyclo[7.3.1.0^{5,13}]trideca-3,5(13),6,8-tetraene-3-carboxamide (CAS 303987-36-2), molecular formula C19H15IN2O3 and molecular weight 446.24 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Hydroxy-N-(4-iodophenyl)-2-oxo-1-azatricyclo[7.3.1.0^{5,13}]trideca-3,5(13),6,8-tetraene-3-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H15IN2O3 |
| Molecular Weight | 446.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 2 |
Related Hydroxy Standards
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Recommended Standards
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- (R)-7-iodo-8-methoxy-1-(1-(pyridin-2-yl)ethyl)-1H-imidazo[4,5-c]quinolin-2(3H)-one (CAS 2443502-86-9)
- N,N'-(Ethane-1,2-diyl)bis(3-chloropropanamide) (CAS 31481-06-8)
- 4-Methylphenyl 5-bromopyridin-2-ylcarbamate (CAS 1984037-66-2)
- Methyl 3-(3-(methylamino)piperidin-1-yl)propanoate (CAS 1251050-56-2)
- (2R,2'R,3R,3'R)-WingPhos (CAS 1884680-45-8)
- 5-Bromo-2-(2-chloro-5-methylphenoxy)aniline (CAS 946664-95-5)
- 3-Phenyl-2-(pyridin-4-yl)pyrrolo[2,1-a]isoquinoline (CAS 31251-31-7)
- 1-(4-Fluorophenyl)-2-(oxetan-3-ylthio)ethan-1-one (CAS 1501864-88-5)
- Carteolol EP Impurity A (CAS 5057-12-5)
- 2-(3,4-Dimethoxybenzoyl)benzoic acid (CAS 51439-85-1)
- Mebendazole EP Impurity D (CAS 132119-11-0)
- Semaglutide Impurity 151 xTFA (CAS CATO-C4X-2226151)
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