4-Chloro-5-(methylamino)-2-(2-oxopropyl)pyridazin-3(2H)-one CAS 303987-67-9
| CAS No. | 303987-67-9 |
| Molecular Formula | C8H10ClN3O2 |
| Molecular Weight | 215.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-Chloro-5-(methylamino)-2-(2-oxopropyl)pyridazin-3(2H)-one is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 4-Chloro-5-(methylamino)-2-(2-oxopropyl)pyridazin-3(2H)-one (CAS 303987-67-9), a certified reference material (molecular formula C8H10ClN3O2, MW 215.64 g/mol) for analytical method development and quality control.
Structurally, 4-Chloro-5-(methylamino)-2-(2-oxopropyl)pyridazin-3(2H)-one (C8H10ClN3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 215.64 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-Chloro-5-(methylamino)-2-(2-oxopropyl)pyridazin-3(2H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H10ClN3O2 |
| Molecular Weight | 215.64 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 7-Chloro-5H-indeno[1,2-b]pyridin-5-one (CAS 101419-81-2)
- 4-Chloro-6-(morpholin-4-yl)-1,3,5-triazin-2-amine (CAS 114209-49-3)
- 7-Chloro-5H-indeno[1,2-c]pyridin-5-one (CAS 114995-34-5)
- 2-Chloro-n,n,6-trimethyl-3-nitropyridin-4-amine (CAS 1196153-08-8)
- 6-Chloro-[3,3'-bipyridine]-5-carbonitrile (CAS 1214346-69-6)
- 6-Chloro-2-phenylpyrimidine-4-carbonitrile (CAS 1242268-11-6)
- Methyl (6-chloro-2-methylpyrimidin-4-yl)glycinate (CAS 1250513-70-2)
- 2'-Chloro-[3,4'-bipyridine]-3'-carbonitrile (CAS 1267007-94-2)
Recommended Standards
- 4-Chloro-2-phenylpyrimidine-5-carbonitrile (CAS 33089-16-6)
- 4-Chloro-5-morpholinopyridazin-3-ol (CAS 944-88-7)
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- 5-(4-Chlorophenyl)pyrimidine-2-carbonitrile (CAS 625451-84-5)
- 215186-99-5 Allyltris(1H,1H,2H,2H-perfluorohexyl)stannane Allyltris(3,3,4,4,5,5,6,6,6-nonafluorohexyl)stannane Tris(1H,1H,2H,2H-perfluorohexyl)allyltin (CAS 215186-99-5)
- 1-(2-Methoxyethyl)cyclopropan-1-amine hydrochloride (CAS 1993247-86-1)
- 6-Methyl-4-thioxo-3,4-dihydropyrimidin-2(1H)-one (CAS 638-13-1)
- (E)-2-((5-bromo-2-hydroxybenzylidene)amino)isoindoline-1,3-dione (CAS 98841-63-5)
- Methyl 4-Amino-3,5-dibromobenzoate (CAS 3282-10-8)
- 1-(Ethylthio)-2-methylpropan-2-ol (CAS 27998-55-6)
- 1-(2,3-Dihydrobenzofuran-5-yl)-2-methylpropan-1-amine (CAS 1021041-90-6)
- Tert-butyl 4-(1-cyanopropylidene)piperidine-1-carboxylate (CAS 1198283-75-8)
- tert-Butyl (3R)-3-sulfanylpiperidine-1-carboxylate (CAS 1202761-09-8)
- [His]1-Acetylated Semaglutide (CAS CATO-C4X-2226219)
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